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Synthesis 2003(13): 2027-2032
DOI: 10.1055/s-2003-41449
DOI: 10.1055/s-2003-41449
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of 2,3-Disubstituted 5,6,7,8-Tetrahydronaphthyls and Related Structures via Diels-Alder Reaction
Further Information
Received
27 March 2003
Publication Date:
10 September 2003 (online)
Publication History
Publication Date:
10 September 2003 (online)
Abstract
A variety of 2,3-disubstituted 5,6,7,8-tetrahydronaphthyl analogues have been synthesized via vinylation of cyclic ketones, subsequent lactonisation and thermally induced, inverse electron demand hetero Diels-Alder reaction. The diversity of the obtained products derives from the multiplicity of cyclic ketones and from the variety of dienophiles of the Diels-Alder reaction.
Key words
condensation - ketones - lactones - bicyclic compounds - Diels-Alder reaction
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References
Commercially available from Fluka.