Direct Conversion of Amidoximes to Amidines via Transfer Hydrogenation

Mariappan Anbazhagan; David W. Boykin; Chad E. Stephens

doi:10.1055/s-2003-42410

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Synthesis 2003(16): 2467-2469
DOI: 10.1055/s-2003-42410

SHORTPAPER

Direct Conversion of Amidoximes to Amidines via Transfer Hydrogenation

Mariappan Anbazhagan, David W. Boykin, Chad E. Stephens*
Department of Chemistry, Georgia State University, Atlanta, Georgia, 30303, USA
Fax: +1(404)6511416; e-Mail: checes@panther.gsu.edu;

Further Information

Publication History

Received 25 June 2003
Publication Date:
29 September 2003 (online)

Abstract
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Abstract

Amidoximes, O-alkylamidoximes, and O-acylamidoximes are directly converted to amidines by reaction with ammonium formate and Pd/C in acetic acid.

Keywords

amidines - amidoximes - reductions - hydrogen transfer - protecting groups, ammonium formate

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