Zusammenfassung
Der größte Teil der Bevölkerung ist berechtigt, Früherkennungs-Untersuchungen für Kolorektale Karzinome durchführen zu lassen. Um die Entscheidung für oder gegen eine bestimmte Maßnahme (Stuhltest, Koloskopie) zu erleichtern, wird eine Entscheidungshilfe präsentiert, die auf randomisierten kontrollierten Interventions- sowie epidemiologischen Studien beruht.
Abstract
Faecal-occult-blood testing (FOB) and colonoscopy are now universally available as screening examinations for colorectal carcinoma in Germany. A simple decision-aid is presented showing the effectiveness of either strategy. It can be used in primary care practice to help patients select the course of action most appropriate for them. The decision aid is based on randomised controlled screening trials of FOB and epidemiological studies.
Schlüsselwörter
Kolorektale Karzinome - Diagnose - Früherkennung - Koloskopie - Hämoccult-Test
Key words
Colorectal neoplasms/diagnosis [MeSH] - colorectal neoplasms/prevention and control [MeSH] - mass screening [MeSH] - colonoscopy [MeSH] - fecal occult blood test [nonMeSH]
Literatur
-
1
Kronborg O, Fenger C, Olsen J, Jorgensen O D, Sondergaard O.
Randomised study of screening for colorectal cancer with faecal-occult-blood test.
Lancet.
1996;
348
1467-1471
-
2
Towler B, Irwig L, Glasziou P, Kewenter J, Weller D, Silagy C.
A systematic review of the effects of screening for colorectal cancer using the faecal occult blood test, hemoccult.
BMJ.
1998;
317
559-565
-
3
Mandel J S, Bond J H, Church T R, Snover D C, Bradley G M, Schuman L M. et al .
Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study.
N Engl J Med.
1993;
328
1365-1371
-
4
Lang C A, Ransohoff D F.
Fecal occult blood screening for colorectal cancer. Is mortality reduced by chance selection for screening colonoscopy?.
JAMA.
1994;
271
1011-1013
-
5
Misra T, Lalor E, Fedorak R N.
Endoscopic perforation rates at a Canadian university teaching hospital.
Can J Gastroenterol.
2004;
18
221-226
-
6
Froehlich F, Gonvers J J, Vader J P, Dubois R W, Burnand B.
Appropriateness of gastrointestinal endoscopy: risk of complications.
Endoscopy.
1999;
31
684-686
-
7
Black W C, Haggstrom D A, Welch H G.
All-cause mortality in randomized trials of cancer screening.
J Natl Cancer Inst.
2002;
94
167-173
Prof. Dr. med. Norbert Donner-BanzhoffMHSc
Abteilung für Allgemeinmedizin, Rehabilitative und Präventive Medizin · Universität Marburg
35033 Marburg
Phone: 0 64 21/28-6 51 20
Fax: 0 64 21/28-6 51 21
Email: norbert@med.uni-marburg.de