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Synlett 2005(6): 0943-0946
DOI: 10.1055/s-2005-864809
DOI: 10.1055/s-2005-864809
LETTER
© Georg Thieme Verlag Stuttgart · New York
Efficient One-Pot Synthesis of 1,2,3-Triazoles from Benzyl and Alkyl Halides
Weitere Informationen
Received
21 December 2004
Publikationsdatum:
23. März 2005 (online)
Publikationsverlauf
Publikationsdatum:
23. März 2005 (online)
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Abstract
An efficient one-pot method for the preparation of 1,2,3-triazoles by 1,3-dipolar cycloaddition of in situ generated azides and alkynes is presented. This facile method can be applied to benzyl or alkyl halides and pure products are isolated by simple filtration.
Key words
1,3-dipolar cycloadditon - click chemistry - 1,2,3-triazoles - one-pot synthesis
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References
Progress of the reaction can be monitored by TLC.