Abstract
Total synthesis of four analogue terpenoids isolated from Caulerpa taxifolia was achieved in good yield with a total control of each double bond. Biological tests to compare the activities of in vitro tubulin polymerisation between the natural caulerpenyne and the synthetic caulerpenyne and its derivatives were also performed.
Key words
total synthesis - caulerpenyne - dihydrorhipocephalin - furocaulerpin - terpenoids - microtubule polymerisation
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