Palladium-Catalyzed Cross-Coupling Reactions of Paramagnetic Vinyl Bromides and Paramagnetic Boronic Acids

Tamás Kálai; József Jekő; Zoltán Berente; Kálmán Hideg

doi:10.1055/s-2006-926279

PAPER

Palladium-Catalyzed Cross-Coupling Reactions of Paramagnetic Vinyl Bromides and Paramagnetic Boronic Acids

Tamás Kálai^a, József Jekő^b, Zoltán Berente^c, Kálmán Hideg*^a
^a Institute of Organic and Medicinal Chemistry, University of Pécs, P. O. Box 99, 7602 Pécs, Hungary
Fax: +36(72)536219; e-Mail: kalman.hideg@aok.pte.hu;
^b ICN, Hungary, P.O. Box 1, 4440 Tiszavasvári, Hungary
^c Institute of Biochemistry and Medical Chemistry, University of Pécs, P. O. Box 99, 7602 Pécs, Hungary

Abstract

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Abstract

Suzuki reactions are utilized for the synthesis of heterobifunctional cross-linking reagents (thiol- or aminospecific and photoactivatable), polyaromatics (such as phenanthrene) and heterocycles (such as coumarin and quinoline), anellated nitroxides and paramagnetic, biologically active molecules (such as cis-stilbene and nicotinamide). Furthermore, the synthesis of new vinyl and allyl boronic acid esters is also reported.

Key words

boron - cross-coupling - free radicals - heterocycles - palladium

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