Aminoalkylation of ‘Push-Pull’ Enamines Having a Methyl Group at the α-Position with Imines of Methyl 3,3,3-Trifluoropyruvate

Abstract

The reaction of ‘push-pull’ enamines having a methyl group at the α-position with imines of methyl 3,3,3-trifluoropyruvate was investigated. Structural sensitivity of the reaction was found and discussed. As a result, a set of β-dicarbonyl compounds bearing a protected amino acid moiety was obtained.

Key words

‘push-pull’ enamines - imines of methyl 3,3,3-trifluoropyruvate - aminoalkylation - protected amino acids

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