Endoskopie heute 2006; 19(3): 165-172
DOI: 10.1055/s-2006-942252
Übersicht

© Georg Thieme Verlag Stuttgart · New York

Divertikulitis: OP-Indikation und Zeitpunkt des operativen Eingriffs

Diverticulitis: Indication and Timing of SurgeryC.-T. Germer1 , C. Jurowich1 , C. Isbert1
  • 1Klinik für Allgemein-, Viszeral- und Thoraxchirurgie, Klinikum Nürnberg Nord
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
12. Oktober 2006 (online)

Zusammenfassung

Voraussetzung für das Stellen einer Operationsindikation bei der Divertikelkrankheit des Kolons ist die Kenntnis des Spontanverlaufs der Erkrankung in Abhängigkeit des Ausprägungsgrades sowie des Verlaufs nach konservativer und operativer Therapie. Darüber hinaus ist ein prätherapeutisch anwendbares Klassifikationssystem der Divertikelkrankheit für eine stadienabhängige chirurgische Therapie unverzichtbar. Die blande Divertikulose (Stadium 0) und die unkomplizierte Divertikulitis (Stadium I) stellen in der Regel keine OP-Indikation dar. Bei bestimmten Risikogruppen (z. B. immunsupprimierte Patienten) sollte bereits nach dem ersten entzündlichen Schub einer unkomplizierten Divertikulitis operiert werden. Bei Vorliegen einer akuten komplizierten Divertikulitis (Stadium II) ist generell eine OP-Indikation gegeben. In Abhängigkeit von Art der Komplikation und klinischem Bild ist der OP-Zeitpunkt für die akute komplizierte Divertikulitis notfallmäßig oder frühelektiv nach initial konservativer und/oder interventioneller Therapie festzulegen. Die chronisch-rezidivierende Divertikulitis (Stadium III) kann ebenfalls eine OP-Indikation darstellen. Der OP-Zeitpunkt sollte nach individuellen Gesichtspunkten unter Berücksichtigung des Beschwerdebildes und der Komorbidität festgelegt werden. Eine generelle Empfehlung zur elektiven Intervalloperation nach dem zweiten entzündlichen Schub kann nach derzeitigem Kenntnisstand nicht mehr gegeben werden.

Abstract

The indication for surgery in diverticular disease is based on knowledge of the natural history of the disease, its course after conservative and operative therapy and the individual risk factors for complicated diverticular disease. Clinically pragmatic pretreatment staging is thus a prerequisite for stage-adapted therapy. Elective sigmoid colectomy is not indicated for bland diverticulosis or after recovery from acute uncomplicated diverticulitis. However immunosuppressed or immunocompromised patients are more likely to fail medical management. For these patients surgery is recommended after recovery from first attack of uncomplicated diverticulitis. Furthermore surgery is generally indicated for acute complicated diverticulitis. Decisive in establishing the indication for surgery is therefore the precise pretherapeutic differentiation of complicated and uncomplicated diverticulitis. Depending on the type of complication and the clinical appearance, the time for surgery of acute complicated diverticulitis is fixed on an emergency or early elective basis following initial conservative and/or interventional therapy. Chronically recurrent diverticulitis may be likewise an indication for elective sigmoid colectomy. The decision to recommend surgery should be influenced by the age and medical condition of the patient as well as by the frequency and serverity of the attacks. The number of attacks of uncomplicated diverticulitis is not necessarily a factor in defining the indication for surgery.

Literatur

  • 1 Aldoori W H, Giovannucci E L, Rimm E B. et al . Use of acetaminophen and nonsteroidal anti-inflammatory drugs: a prospective study and the risk of symptomatic diverticular disease in men.  Arch Fam Med. 1998;  7 255-260
  • 2 Ambrosetti P, Chautems R, Soravia C. et al . Long-term outcome of mesocolic and pelvic diverticular abscesses of the left Colon: a prospective study of 73 cases.  Dis Colon Rectum. 2005;  48 787-791
  • 3 Ambrosetti P, Grossholz M, Becker C. et al . Computed tomography in acute left colonic diverticulitis.  Br J Surg. 1997;  84 532-534
  • 4 Ambrosetti P, Morel P. Acute left-sided colonic diverticulitis: diagnosis and surgical indications after successful conservative therapy of first time acute diverticulitis.  Zentralbl Chir. 1998;  123 1382-1385
  • 5 Ambrosetti P, Robert J H, Witzig J A. et al . Acute left colonic diverticulitis in young patients.  J Am Coll Surg. 1994;  179 156-160
  • 6 Anaya D A, Flum D R. Risk of emergency colectomy and colostomy in patients with diverticular disease.  Arch Surg. 2005;  140 681-685
  • 7 Benoist S, Panis Y, Pannegeon V. et al . Can failure of percutaneous drainage of postoperative abdominal abscesses be predicted?.  Am J Surg. 2002;  184 148-153
  • 8 Bergamaschi R, Arnaud J P. Anastomosis level and specimen length in surgery for uncomplicated diverticulitis of the sigmoid.  Surg Endosc. 1998;  12 1149-1151
  • 9 Bramley P N, Masson J W, McKnight G. et al . The role of an open-access bleeding unit in the management of colonic haemorrhage. A 2-year prospective study.  Scand J Gastroenterol. 1996;  31 764-769
  • 10 Broderick-Villa G, Burchette R J, Collins J C. et al . Hospitalization for acute diverticulitis does not mandate routine elective colectomy.  Arch Surg. 2005;  140 576-581
  • 11 Chapman J, Davies M, Wolff B. et al . Complicated diverticulitis: is it time to rethink the rules?.  Ann Surg. 2005;  242 576-581
  • 12 Chapman J R, Dozois E J, Wolff B G. et al . Diverticulitis: a progressive disease? Do multiple recurrences predict less favorable outcomes?.  Ann Surg. 2006;  243 876-830
  • 13 Cunningham M A, Davis J W, Kaups K L. Medical versus surgical management of diverticulitis in patients under age 40.  Am J Surg. 1997;  174 733-735
  • 14 Elliott T B, Yego S, Irvin T T. Five-year audit of the acute complications of diverticular disease.  Br J Surg. 1997;  84 535-539
  • 15 Farmakis N, Tudor R G, Keighley M R. The 5-year natural history of complicated diverticular disease.  Br J Surg. 1994;  81 733-735
  • 16 Farthmann E H, Ruckauer K D, Häring R U. Evidence-based surgery: diverticulitis - a surgical disease?.  Langenbecks Arch Surg. 2000;  385 143-151
  • 17 Germer C T, Buhr H J. Sigmoid diverticulitis. Surgical indications and timing.  Chirurg. 2002;  73 681-689
  • 18 Hansen O, Stock W. Prophylaktische Operation bei der Divertikelkrankheit des Kolons - Stufenkonzept durch exakte Stadieneinteilung.  Langenbecks Arch Chir (Suppl II). 1999;  1257-1260
  • 19 Hart A R, Kennedy H J, Stebbings W S. et al . How frequently do large bowel diverticula perforate? An incidence and cross-sectional study.  Eur J Gastroenterol Hepatol. 2000;  12 661-665
  • 20 Hinchey E J, Schaal P G, Richards G K. Treatment of perforated diverticular disease of the colon.  Adv Surg. 1978;  12 85-109
  • 21 Janes S, Meagher A, Frizelle F A. Elective surgery after acute diverticulitis.  Br J Surg. 2005;  92 133-142
  • 22 Jensen D M, Machicado G A, Jutabha R. et al . Urgent colonoscopy for the diagnosis and treatment of severe diverticular hemorrhage.  N Engl J Med. 2000;  342 78-82
  • 23 Köhler L, Sauerland S, Neugebauer E. The Scientific Committee of the European Association for Endoscopic Surgery . Diagnosis and treatment of diverticular disease: results of a consensus development conference.  Surg Endosc. 1999;  13 430-436
  • 24 Kumar R R, Kim J T, Haukoos J S. et al . Factors affecting the successful management of intra-abdominal abscesses with antibiotics and the need for percutaneous drainage.  Dis Colon Rectum. 2006;  49 183-189
  • 25 Longstreth G F. Epidemiology and outcome of patients hospitalized with acute lower gastrointestinal hemorrhage: a population-based study.  Am J Gastroenterol. 1997;  92 419-424
  • 26 Lorimer J W. Is prophylactic resection valid as an indication for elective surgery in diverticular disease?.  Can J Surg. 1997;  40 445-448
  • 27 Marinella M A, Mustafa M. Acute diverticulitis in patients 40 years of age and younger.  Am J Emerg Med. 2000;  18 140-142
  • 28 Morton D G, Keighley M R. Prospective national study of complicated diverticulitis in Great Britain.  Chirurg. 1995;  66 1173-1176
  • 29 Mueller M H, Glatzle J, Kasparek M S. et al . Long-term outcome of conservative treatment in patients with diverticulitis of the sigmoid colon.  Eur J Gastroenterol Hepatol. 2005;  17 649-654
  • 30 Nylamo E. Diverticulitis of the colon: role of surgery in preventing complications.  Ann Chir Gynaecol. 1990;  79 139-142
  • 31 Parks T G. Natural history of diverticular disease of the colon. A review of 521 cases.  BMJ. 1969;  iv 639-642
  • 32 Peura D A, Lanza F L, Gostout C J. et al . The American College of Gastroenterology Bleeding Registry: preliminary findings.  Am J Gastroenterol. 1997;  92 924-928
  • 33 Rafferty J, Shellito P, Hyman N H. et al . Standards Committee of American Society of Colon and Rectal Surgeons. Practice parameters for sigmoid diverticulitis.  Dis Colon Rectum. 2006;  49 939-944
  • 34 Reifferscheid M. Early resection in diverticulitis.  Langenbecks Arch Chir. 1976;  342 439-444
  • 35 Salem L, Veenstra D L, Sullivan S D. et al . The timing of elective colectomy in diverticulitis: a decision analysis.  J Am Coll Surg. 2004;  199 904-912
  • 36 Schoetz Jr  D J. Diverticular disease of the colon: a century-old problem.  Dis Colon Rectum. 1999;  42 703-709
  • 37 Siewert J R, Huber F T, Brune I B. Early elective surgery of acute diverticulitis of the colon.  Chirurg. 1995;  66 1182-1189
  • 38 Somasekar K, Foster M E, Haray P N. The natural history diverticular disease: is there a role for elective colectomy?.  J R Coll Surg Edinb. 2002;  47 481-482
  • 39 Stollman N H, Raskin J B. Diagnosis and management of diverticular disease of the colon in adults. Ad Hoc Practice Parameters Committee of the American College of Gastroenterology.  Am J Gastroenterol. 1999;  94 3110-3121
  • 40 Thaler K, Weiss E G, Nogueras J J. et al . Recurrence rates at minimum 5-year follow-up: laparoscopic versus open sigmoid resection for uncomplicated diverticulitis.  Surg Laparosc Endosc Percutan Tech. 2003;  13 325-327
  • 41 Wolff B G, Ready R L, MacCarty R L. et al . Influence of sigmoid resection on progression of diverticular disease of the colon.  Dis Colon Rectum. 1984;  27 645-647
  • 42 Wong W D, Wexner S D, Lowry A. et al . Practice parameters for the treatment of sigmoid diverticulitis - supporting documentation. The Standards Task Force. The American Society of Colon and Rectal Surgeons.  Dis Colon Rectum. 2000;  43 290-297
  • 43 Young-Fadok T M, Roberts P L, Spencer M P. et al . Colonic diverticular disease.  Curr Probl Surg. 2000;  37 457-514

Prof. Dr. C.-T. Germer

Klinik für Allgemein-, Viszeral- und Thoraxchirurgie Klinikum Nürnberg Nord

Prof.-Ernst-Nathan-Str. 1

90419 Nürnberg

eMail: Germer@klinikum-nuernberg.de