Abstract
ω-Aminodithioester derivatives were obtained from thionolactams by reaction with an
alkyl triflate followed by thiolysis with hydrogen sulfide. The presence of an electron-withdrawing
group was required on the N1 position (p -nitrophenyl or benzoyl) to favor the ring opening of γ-, δ- and ε-thionolactams.
In the case of β-thionolactam, activation was provided by a CF2 motif in C3 position
Key words
dithioesters - thionolactams - thioamidinium salts - thio-Pinner reaction
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