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Pneumologie 2007; 61(1): 41-45
DOI: 10.1055/s-2006-955002
Übersicht
© Georg Thieme Verlag Stuttgart · New York

Aviäre Influenza und das Schwere Akute Respiratorische Syndrom (SARS) - Erfahrungen und Perspektiven

Avian Influenza and the Severe Acute Respiratory Syndrome (SARS) - Experiences and PerspectivesG.  Hoheisel1 , W.  K.  Luk2 , J.  Winkler3 , H.  Wirtz4 , A.  Gillissen5 , D.  S.  Hui6 , U.  G.  Liebert7
  • 1Pneumologisch-Allergologische Praxis, Leipzig
  • 2Department of Microbiology, Tseung Kwan O Hospital, Tseung Kwan O, Kowloon, Hong Kong SAR, People's Republic of China
  • 3Pneumologisch-Allergologische Praxis, Leipzig
  • 4Medizinische Klinik und Poliklinik I, Abteilung Pneumologie, Universität Leipzig, Leipzig
  • 5Robert Koch-Klinik, Leipzig
  • 6Department of Medicine and Therapeutics, Pulmonary Division, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, People's Republic of China
  • 7Institut für Virologie, Universität Leipzig, Leipzig
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Publication History

eingereicht 28.9.2006

akzeptiert 21.11.2006

Publication Date:
23 January 2007 (online)

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Zusammenfassung

Neue respiratorische Viren wurden in den letzten Jahren im Zusammenhang mit Pneumonien beim Menschen nachgewiesen. Das plötzliche Erscheinen des schweren akuten respiratorischen Syndroms (SARS) im Jahr 2003 zeigte, dass eine neue und hoch infektiöse, durch ein bisher nicht bekanntes Virus verursachte Erkrankung in der Lage war, sich rasch auszubreiten, durch stringente Maßnahmen jedoch kontrolliert werden konnte. Das aviäre Influenza A-H5N1-Virus hoher Pathogenität hat in zahlreichen Fällen die Spezies-Barriere zwischen Menschen, Säugetieren und Vögeln übersprungen und stellt eine ernstzunehmende pandemische Bedrohung dar. Die Anwendung des bisher Gelernten und die Weiterentwicklung präventiver Strategien, effizienter Vakzine und antiviraler Substanzen sind neben weltweiter Überwachungsmaßnahmen entscheidend um ein erneutes, verstärktes oder erstmaliges Erscheinen von viralen Krankheitserregern wie des SARS-CoV, Influenza A-H5N1-Virus oder neuer Viren rasch zu erkennen, deren Ausbreitung einzudämmen und sie zu besiegen.

Abstract

New respiratory viruses associated with pneumonia have in the past few years been detected in humans. The sudden appearance of the severe acute respiratory syndrome (SARS) in 2003 demonstrated that an emerging and highly infectious disease caused by a hitherto unknown virus was able to spread rapidly, but could finally be contained by stringent measures. The avian influenza A-H5N1-virus of high pathogenicity has crossed in multiple instances the species barriers between humans, mammals, and birds posing a serious pandemic threat. The application of the so far learnt and the continued development of preventive strategies, efficient vaccines, and antiviral substances are besides worldwide surveillance decisive to rapidly detect the repeated, enforced, or new appearance of viruses like the SARS-CoV, influenza A-H5N1 virus, or of new viruses, to contain their spread, and to defeat them.

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Priv.-Doz. Dr. med. Gerhard Hoheisel

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04275 Leipzig

Email: gerhard.hoheisel@t-online.de