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Planta Med 1990; 56(2): 218-221
DOI: 10.1055/s-2006-960929
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© Georg Thieme Verlag Stuttgart · New York

Steroidal Sapogenins from Tacca leontopetaloides

Abdallah M. E. Abdel-Aziz1 , 2 , Keith R. Brain1 , Gerald Blunden3 , Trevor Crabb4 , Ahmed K. Bashir5
  • 1Welsh School of Pharmacy, UWCC, PO Box 13, Cardiff CF1 3XF, U.K.
  • 2Juba University, Khartoum Centre, PO Box 321/1, Khartoum, Sudan
  • 3School of Pharmacy and Biomedical Sciences, Portsmouth Polytechnic, Portsmouth PO1 1DZ, U.K.
  • 4Department of Chemistry, Portsmouth Polytechnic, Portsmoth PO1 1DZ, U.K.
  • 5National Council for Research, PO Box 2404, Khartoum, Sudan
Further Information

Publication History

1989

Publication Date:
05 January 2007 (online)

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Abstract

Diosgenin and its ring-F-hydroxylated derivatives isonarthogenin {spirost-5-ene-3,27-diol {3β, 22R, 25S)} and isonuatigenin {spirost-5-ene-3,25-diol (3β, 22R, 25S)}, together with the 22,25-epoxyfurost-5-ene isomer nuatigenin {furost-5-ene-3,26-diol-22,25-epoxy (3β, 22R, 25S)}, were identified as the major steroidal sapogenins of the acid hydrolysate of an extract of leaves of Tacca leontopetaloides by IR, 1H-NMR, 13C-NMR, and mass spectroscopy. A diosgenin ester was isolated which apparently arose by ring closure of a glycosylated furostene during hydrolysis.

Key words

Tacca leontopetaloides - steroidal sapogenins - diosgenin - isonarthogenin - molluscicidal activity