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Synthesis 2007(10): 1471-1474
DOI: 10.1055/s-2007-966044
DOI: 10.1055/s-2007-966044
PAPER
© Georg Thieme Verlag Stuttgart · New YorkA New Chemoselective Synthesis of Brombuterol
Weitere Informationen
Received
21 December 2006
Publikationsdatum:
02. Mai 2007 (online)
Publikationsverlauf
Publikationsdatum:
02. Mai 2007 (online)
Abstract
A practical method for the synthesis of brombuterol [1-(4-amino-3,5-dibromophenyl)-2-(tert-butylamino)ethanol] in high overall yield is described starting from 4′-aminoacetophenone using a new chemoselective route.
Key words
β-agonists - chemoselective - bromination - brombuterol - clembuterol
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