Semin Thromb Hemost 2007; 33(2): 144-150
DOI: 10.1055/s-2007-969027
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

The Active Platelet: Translation and Protein Synthesis in an Anucleate Cell

Stephan Lindemann1 , Meinrad Gawaz1
  • 1Medizinische Klinik III, Eberhard Karls-Universität Tübingen, Tübingen, Germany
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Publikationsdatum:
06. März 2007 (online)

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ABSTRACT

Platelets are the major cellular component of the hemostatic system that controls vessel and wound repair. However, platelets also have a variety of additional functions in inflammatory responses and host defense. The function and structure of the platelet was assumed to be very simple for a long period of time. With more modern tools of investigation such as cDNA arrays and proteomics, we have discovered a cell that is becoming a more sophisticated libero that functions in the classic mechanisms of white blood cells-inflammation and immunity.

REFERENCES

Stephan LindemannM.D. 

Medizinische Klinik III, Eberhard Karls Universität Tübingen

Otfried-Müller-Str. 10, D-72076 Tübingen, Germany

eMail: stephan.lindemann@med.uni-tuebingen.de