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DOI: 10.1055/s-2007-969027
The Active Platelet: Translation and Protein Synthesis in an Anucleate Cell
Publication History
Publication Date:
06 March 2007 (online)
ABSTRACT
Platelets are the major cellular component of the hemostatic system that controls vessel and wound repair. However, platelets also have a variety of additional functions in inflammatory responses and host defense. The function and structure of the platelet was assumed to be very simple for a long period of time. With more modern tools of investigation such as cDNA arrays and proteomics, we have discovered a cell that is becoming a more sophisticated libero that functions in the classic mechanisms of white blood cells-inflammation and immunity.
KEYWORDS
Platelets - translation - proteomics - cDNA
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Stephan LindemannM.D.
Medizinische Klinik III, Eberhard Karls Universität Tübingen
Otfried-Müller-Str. 10, D-72076 Tübingen, Germany
Email: stephan.lindemann@med.uni-tuebingen.de