ABSTRACT
Pancreatic islet cell transplantation is an evolving treatment of severe, refractory
type 1 diabetes that has been gaining more use, particularly after one year rates
of insulin independence post-transplantation were found to approach 80% under the
Edmonton protocol. Islet cell transplantation involves percutaneous delivery of harvested
allogeneic β cells into the portal venous circulation for implantation into the liver.
We present the case of a 35-year-old woman with type 1 diabetes and situs ambiguous
with left isomerism and resultant variant anatomy of her portal venous anatomy who
underwent islet cell transplantation, which, to our knowledge, has not been previously
reported.
KEYWORDS
Pancreatic islet cell transplantation - situs ambiguous - treatment of diabetes mellitus
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Rajesh ShahM.D.
Department of Radiology, University of Illinois Medical Center at Chicago
1740 West Taylor Street, MC 931, Chicago, IL 60612
