Semin Hear 2007; 28(2): 120-132
DOI: 10.1055/s-2007-973438
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Training-Related Changes in the Brain: Evidence from Human Auditory-Evoked Potentials

Kelly L. Tremblay1
  • 1Associate Professor, Department of Speech and Hearing Sciences, University of Washington, Seattle, Washington
Further Information

Publication History

Publication Date:
23 April 2007 (online)

ABSTRACT

Auditory-evoked potentials are being used to examine training-related changes in the human central auditory system, and there is converging evidence that focused listening training, using various training methods and different types of stimuli alters evoked neural activity. Such training-related changes are often described in terms of physiological plasticity, a process whereby the neural representation of the acoustic cue is modified with training. In this review, the concept of plasticity is discussed from a broader perspective. Specifically addressed is how electrophysiological methods are being used to study physiological modifications that occur with training, and how this information might contribute to the rehabilitation of people who wear hearing aids and cochlear implants.

REFERENCES

  • 1 Eggermont J J. The correlative brain: theory and experiment. In: Friston KJ Neutral Interaction (Studies of Brain Function). New York; Springer-Verlag 1990: 1-36
  • 2 Steinschneider M, Schroeder C E, Arezzo J C, Vaughan H G. Physiologic correlates of the voice onset time boundary in primary auditory cortex (A1) of the awake monkey: temporal response patterns.  Brain Lang. 1995;  48(3) 326-340
  • 3 Steinschneider M, Reser D, Schroeder C E, Arezzo J C. Tonotopic organization of responses reflecting stop consonant place of articulation in primary auditory cortex (A1) of the monkey.  Brain Res. 1995;  674(1) 147-152
  • 4 Steinschneider M, Arezzo J, Vaughan J HG. Speech evoked activity in the auditory radiations and cortex of the awake monkey.  Brain Res. 1982;  252(2) 353-365
  • 5 Steinschneider M, Volkov I O, Noh M D, Garell P C, Howard M A. Temporal encoding of the voice-onset-time phonetic parameter by field potentials recorded directly from human auditory cortex.  J Neurophysiol. 1999;  82(5) 2346-2357
  • 6 Phillips D P, Hall S E. Response timing constraints on the cortical representation of sound time structure.  J Acoust Soc Am. 1990;  88(3) 1403-1411
  • 7 Ahissar E, Nagarajan S, Ahissar M et al.. Speech comprehension is correlated with temporal response patterns recorded from auditory cortex.  Proc Natl Acad Sci USA. 2001;  98(23) 13367-13372
  • 8 Schreiner C E, Mendelson J, Raggio M W, Brosch M, Krueger K. Temporal processing in cat primary auditory cortex.  Acta Otolaryngol Suppl. 1997;  532 54-60
  • 9 Irvine D RF, Rajan R. Injury-and use-related plasticity in the primary sensory cortex of adult mammals: possible relationship to perceptual learning.  Clin Exp Pharmacol Physiol. 1996;  23(10-11) 939-947
  • 10 Willott J F. Changes in frequency representation in the auditory system of mice with age-related hearing impairment.  Brain Res. 1984;  309(1) 159-162
  • 11 Willott J F. Aging and the Auditory System. San Diego; Singular 1991
  • 12 Javel E, Shepherd R K. Electrical stimulation of the auditory nerve. III. response initiation sites and temporal fine structure.  Hear Res. 2000;  140(1-2) 45-76
  • 13 Shepherd R K, Baxi J H, Hardie N A. Response of inferior colliculus neurons to electrical stimulation of the auditory nerve in neonatally deafened cats.  J Neurophysiol. 1999;  82(3) 1363-1380
  • 14 Kral A, Hartmann R, Tillein J, Heid S, Klinke R. Hearing after congenital deafness: central auditory plasticity and sensory deprivation.  Cereb Cortex. 2002;  12(8) 797-807
  • 15 Chang E F, Merzenich M M. Environmental noise retards auditory cortical development.  Science. 2003;  300(5618) 498-502
  • 16 Stelmachowicz P G, Kopun J, Mace A, Lewis D E. The perception of amplified speech by listeners with hearing loss: acoustic correlates.  J Acoust Soc Am. 1995;  98(3) 1388-1399
  • 17 Tyler R S, Summerfield A Q. Cochlear implantation: relationships with research on auditory deprivation and acclimatization.  Ear Hear. 1996;  17(3 Suppl) 38s-50s
  • 18 Watson C S. Auditory perceptual learning and the cochlear implant.  Am J Otol. 1991;  12(Suppl) 73-79
  • 19 Robinson K, Summerfield A Q. Adult auditory learning and training.  Ear Hear. 1996;  17(3 Suppl) 51S-65S
  • 20 Robinson K, Gatehouse S. The time course of effects on intensity discrimination following monaural fitting of hearing aids.  J Acoust Soc Am. 1996;  99(2) 1255-1258
  • 21 Bakin J S, Weinberger N M. Classical conditioning induces CS specific receptive field plasticity in the auditory cortex of the guinea pig.  Brain Res. 1990;  536(1-2) 271-286
  • 22 Barlow H B, Foldiak P. Adaptation and decorrelation in the cortex. In: Miall RMD, Mitchison, GJ The Computing Neuron. New York; Addison-Wesley 1989: 54-72
  • 23 Tremblay K. Beyond the ear: physiological perspectives on auditory rehabilitation.  Semin Hear. 2005;  26(3) 127-136
  • 24 Tremblay K. Page ten. Hearing aids and the brain: what's the connection?.  Hearing J. 2006;  59 10-16
  • 25 Neuman A C. Central auditory system plasticity and aural rehabilitation of adults.  J Rehabil Res Dev. 2005;  42(4, Suppl 2) 169-186
  • 26 Tremblay K L. Central auditory plasticity: implications for auditory rehabilitation.  The Hearing Journal. 2003;  56(1) 10-17
  • 27 Tremblay K L, Kraus N. Auditory training induces asymmetrical changes in cortical neural activity.  J Speech Lang Hear Res. 2002;  45(3) 564-572
  • 28 Willott J F. Physiological plasticity in the auditory system and its possible relevance to hearing aid use, deprivation effects, and acclimatization.  Ear Hear. 1996;  17(3 Suppl) S66-S77
  • 29 Souza P E, Tremblay K L. New perspectives on assessing amplification effects.  Trends Amplif. 2006;  10 119-143
  • 30 Alcantara J I, Dooley G J, Blamey P J, Seligman P M. Preliminary evaluation of a formant enhancement algorithm on the perception of speech in noise for normally hearing listeners.  Audiology. 1994;  33(1) 15-27
  • 31 Sweetow R, Palmer C V. Efficacy of individual auditory training in adults: a systematic review of the evidence.  J Am Acad Audiol. 2005;  16(7) 494-504
  • 32 Naatanen R, Picton T. The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure.  Psychophysiology. 1987;  24(4) 375-425
  • 33 Naatanen R. The role of attention in auditory information processing as revealed by event-related potentials and other brain measures of cognitive function.  Behav Brain Sci. 1990;  13(2) 201-288
  • 34 Hall J. Handbook of Auditory Evoked Responses. Boston, MA; Allyn & Bacon 1992
  • 35 Stapells D R. Threshold estimation by the tone-evoked auditory brainstem response: A literature meta-analysis.  J Speech Lang Path Audiol. 2000;  24(2) 74-83
  • 36 Hyde M. The N1 response and its applications.  Audiol Neurootol. 1997;  2(5) 281-307
  • 37 Naatanen R. The mismatch negative (MMN). In: Attention and Brain Function. Hillsdale, NJ; Lawrence Erlbaum 1992: 136-200
  • 38 Steinschneider M, Dunn M. Electrophysiology in Developmental Neuropsychology. 2nd ed. Amsterdam, The Netherlands; Elsevier Science 2002: 91-146
  • 39 Woods D L. The component structure of the N1 wave of the human auditory evoked potential.  Electroencephalogr Clin Neurophysiol Suppl. 1995;  44 102-109
  • 40 Burkard R, Don M, Eggermont J. Auditory Evoked Potentials: Basic Principles and Clinical Application. 1st ed. Philadelphia; Lippincott Williams & Wilkins 2006
  • 41 Martin B A, Tremblay K, Stapells D R. Principles and applications of cortical evoked potentials. In: Burkard R, Don M, Eggermont J Auditory Evoked Potentials: Basic Principles and Clinical Application 1st ed. Philadelphia, PA; Lippincott Williams & Wilkins 2006: 482-507
  • 42 Kraus N, McGee T, Carrell T, King C, Tremblay K, Nicol N. Central auditory system plasticity associated with speech discrimination training.  J Cogn Neurosci. 1995;  7 27-32
  • 43 Tremblay K, Kraus N, Carrell T D, McGee T. Central auditory system plasticity: generalization to novel stimuli following listening training.  J Acoust Soc Am. 1997;  102(6) 3762-3773
  • 44 McClaskey C L, Pisoni D B, Carrell T D. Transfer of training of a new linguistic contrast in voicing.  Percept Psychophys. 1983;  34(4) 323-330
  • 45 Tremblay K, Kraus N, McGee T. The time course of auditory perceptual learning: neurophysiological changes during speech-sound training.  Neuroreport. 1998;  9(16) 3557-3560
  • 46 Menning H, Roberts L. Pantev, C. Plastic changes in the auditory cortex induced by intensive frequency discrimination training.  Neuroreport. 2000;  11(4) 817-822
  • 47 Menning H, Imaizumi S, Zwitserlood P, Pantev C. Plasticity of the human auditory cortex induced by discrimination learning of non-native, mora-timed contrasts of the Japanese language.  Learn Mem. 2002;  9(5) 253-267
  • 48 Atienza M, Cantero J L, Dominguez-Marin E. The time course of neural changes underlying auditory perceptual learning.  Learn Mem. 2002;  9(3) 138-150
  • 49 Gottselig J M, Brandeis D, Hofer-Tinguely G, Borbely A A, Achermann P. Human central auditory plasticity associated with tone sequence learning.  Learn Mem. 2004;  11(2) 162-171
  • 50 Picton T W, Alain C, Woods D L et al.. Intracerebral sources of human auditory-evoked potentials.  Audiol Neurootol. 1999;  4(2) 64-79
  • 51 Sharma A, Dorman M. Cortical auditory evoked potential correlates of categorical perception of voice-onset-time.  J Acoust Soc Am. 1999;  106(2) 1078-1083
  • 52 Tremblay K L, Piskosz M, Souza P. Aging alters the neural representation of speech-cues.  Neuroreport. 2002;  13(15) 1865-1870
  • 53 Tremblay K L, Piskosz M, Souza P. Effects of age and age-related hearing loss on the neural representation of speech cues.  Clin Neurophysiol. 2003;  114(7) 1332-1343
  • 54 Tremblay K, Kejriwal C, De Nisi J. Auditory training and the N1-P2 complex. Abstract presented at: International Evoked Audiometry Response Study Group Meeting July 22-27, 2001 Vancouver, Canada
  • 55 Tremblay K, Kraus N, McGee T, Ponton C, Otis B. Central auditory plasticity: changes in the N1-P2 complex after speech-sound training.  Ear Hear. 2001;  22(2) 79-90
  • 56 Tremblay K, Kraus N, Carrell T D, McGee T. Central auditory system plasticity: generalization to novel stimuli following listening training.  J Acoust Soc Am. 1997;  102(6) 3762-3773
  • 57 Reinke K S, He Y, Wang C, Alain C. Perceptual learning modulates sensory evoked response during vowel segregation.  Brain Res Cogn Brain Res. 2003;  17(3) 781-791
  • 58 Alain C, Snyder J S, He Y, Reinke K S. Changes in auditory cortex parallel rapid perceptual learning.  Cereb Cortex. 2006;  , in press
  • 59 Bosnyak D J, Eaton R A, Roberts L E. Distributed auditory cortical representations are modified when non-musicians are trained at pitch discrimination with 40 Hz amplitude modulated tones.  Cereb Cortex. 2004;  14(10) 1088-1099
  • 60 Brattico E, Tervaniemi M, Picton T W. Effects of brief discrimination-training on the auditory N1 wave.  Neuroreport. 2003;  14(18) 2489-2492
  • 61 Sheehan K A, McArthur G M, Bishop D V. Is discrimination training necessary to cause changes in the P2 auditory event-related brain potential to speech sounds?.  Brain Res Cogn Brain Res. 2005;  25(2) 547-553
  • 62 Tremblay K L, Billings C J, Friesen L M, Souza P E. Neural representation of amplified speech sounds.  Ear Hear. 2006;  27(2) 93-103
  • 63 Tremblay K L, Friesen L, Martin B A, Wright R. Test-retest reliability of cortical evoked potentials using naturally produced speech sounds.  Ear Hear. 2003;  24(3) 225-232
  • 64 Friesen L M, Tremblay K L. Acoustic change complexes (ACC) recorded in adult cochlear implant listeners.  Ear Hear. 2006;  27 678-685
  • 65 Escera C. New clinical applications of brain evoked potentials: mismatch negativity.  Med Clin (Barc). 1997;  108(8) 701-708
  • 66 Pekkonen E, Rinne T, Naatanen R. Variability and replicability of the mismatch negativity.  Electroencephalogr Clin Neurophysiol. 1995;  96(6) 546-554
  • 67 Paavilainen P, Cammann R, Alho K et al.. Event-related potentials to pitch change in an auditory stimulus sequence during sleep.  Electroencephalogr Clin Neurophysiol Suppl. 1987;  40 246-255
  • 68 Teismann I K, Soros P, Manemann E et al.. Responsiveness to repeated speech stimuli persists in left but not right auditory cortex.  Neuroreport. 2004;  15(8) 1267-1270
  • 69 Hillyard S A, Hink R F, Schwent V L, Picton T W. Electrical signs of selective attention in the human brain.  Science. 1973;  182(108) 177-180
  • 70 Woldorff M G, Hackley S A, Hillyard S A. The effects of channel-selective attention on the mismatch negativity wave elicited by deviant tones.  Psychophysiology. 1991;  28(1) 30-42
  • 71 Alain C, Woods D L. Attention modulates auditory pattern memory as indexed by event-related brain potentials.  Psychophysiology. 1997;  34(5) 534-546
  • 72 Alain C, Izenberg A. Effects of attentional load on auditory scene analysis.  J Cogn Neurosci. 2003;  15(7) 1063-1073
  • 73 Gravel J, Kurtzberg D, Stapells D R, Vaughan H G, Wallace I F. Case studies.  Semin Hear. 1989;  10(3) 272-287
  • 74 Kurtzberg D. Cortical event-related potentials assessment of auditory system function.  Semin Hear. 1989;  10 252-261
  • 75 Kraus N, McGee T. Auditory event-related potentials. In: Katz J Handbook of Clinical Audiology. 4th ed. Baltimore, MD; Williams and Wilkins 1994: 403-406
  • 76 Rapin I. Evoked responses to clicks in a group of children with communication disorders.  Ann NY Acad Sci. 1964;  112 182-203
  • 77 Sharma A, Martin K, Roland P et al.. P1 latency as a biomarker for central auditory development in children with hearing impairment.  J Am Acad Audiol. 2005;  16(8) 564-573
  • 78 Korczak P A, Kurtzberg D, Stapells D R. Effects of sensorineural hearing loss and personal hearing aids on cortical event-related potential and behavioral measures of speech-sound processing.  Ear Hear. 2005;  26(2) 165-185
  • 79 Billings C, Tremblay K L, Souza P E. Effects of amplification and stimulus intensity on cortical auditory evoked potentials.  Audiology Neuro-Otology. 2007;  , in press
  • 80 Tremblay K, Kalstein L, Billings C, Souza P E. The neural representation of consonant-vowel transitions in adults who wear hearing aids.  Trends Amplif. 2006;  10 155-162
  • 81 Adler G, Adler J. Influence of stimulus intensity on AEP components in the 80- to 200- millisecond latency range.  Audiology. 1989;  28(6) 316-324
  • 82 Adler G, Adler J. Auditory stimulus processing at different stimulus intensities as reflected by auditory evoked potentials.  Biol Psychiatry. 1991;  29(4) 347-356
  • 83 Beagley H A, Knight J J. Changes in auditory evoked response with intensity.  J Laryngol Otol. 1967;  81(8) 861-873
  • 84 Beagley H A, Knight J J. The auditory evoked cortical response as an index of hearing in practical audiometry.  J Laryngol Otol. 1967;  81(3) 347-351
  • 85 Martin B A, Boothroyd A. Cortical, auditory, evoked potentials in response to changes of spectrum and amplitude.  J Acoust Soc Am. 2000;  107(4) 2155-2161
  • 86 Picton T W, Goodman W, Bryce D. Amplitude of evoked responses to tones of high intensity.  Acta Otolaryngol. 1970;  70(2) 77-82
  • 87 Rapin I, Schimmel H, Tourk L M, Krasnegor N A, Pollak C. Evoked responses to clicks and tones of varying intensity in waking adults.  Electroencephalogr Clin Neurophysiol. 1966;  21(4) 335-344
  • 88 Carhart R. Auditory Training. New York; Holt, Rinehart and Winston 1960

Kelly L TremblayPh.D. 

Department of Speech and Hearing Sciences University of Washington

1417 NE 42nd St., Seattle, WA 98105

Email: tremblay@u.washington.edu