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Semin Neurol 2007; 27(4): 347-355
DOI: 10.1055/s-2007-985332
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Approach to the Evaluation of Small Fiber Peripheral Neuropathy and Disorders of Orthostatic Intolerance

B.P. Goodman1
  • 1Department of Neurology, Mayo Clinic, Scottsdale, Arizona
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Publication History

Publication Date:
15 August 2007 (online)

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ABSTRACT

Small fiber peripheral neuropathy is a frequently encountered neurological disorder, which can be difficult to diagnose. In this article, the differential diagnosis of small fiber neuropathy is discussed, along with role of autonomic testing, skin biopsy, and quantitative sensory testing, in establishing a definitive diagnosis of small fiber peripheral neuropathy. Disorders of orthostatic intolerance, including postural orthostatic tachycardia syndrome (POTS), are also discussed, emphasizing diagnostic evaluation and a treatment approach to these disorders.

KEYWORDS

Small fiber neuropathy - orthostatic intolerance - postural orthostatic tachycardia syndrome

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B.P. GoodmanM.D. 

Department of Neurology, Mayo Clinic

13400 East Shea Boulevard, Scottsdale, AZ 85259

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