Muscle Channelopathies

ABSTRACT

In recent years the term channelopathy has been adopted to describe neurological disorders caused by mutations in different ion channel genes. Myopathic channelopathies include two main groups: nondystrophic myotonias and periodic paralyses. This article reviews the clinical features, diagnostic approach, molecular causes, and management of patients with nondystrophic myotonias and periodic paralyses.

KEYWORDS

Channelopathies - myotonia congenita - myotonia - paramyotonia - periodic paralysis

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