Dialyse aktuell 2008; 12(1): 52-53
DOI: 10.1055/s-2008-1064893
Markt und Forschung

© Georg Thieme Verlag KG Stuttgart · New York

Selektive Vitamin-D-Rezeptor-Aktivierung - Schutz für Herz, Nieren und Gefäße

Further Information

Publication History

Publication Date:
11 March 2008 (online)

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Paricalcitol, ein Vitamin-D-Rezeptor-Aktivator (VDRA), der zur Therapie des sekundären Hyperparathyreoidismus (sHPT) bei Patienten mit chronischer Nierenerkrankung ("chronic kidney disease", CKD) zugelassen ist, senkt bei den Betroffenen nicht nur das pathologisch erhöhte Parathormon (PTH), sondern auch die Mortalität. Der selektive VDRA (sVDRA) Paricalcitol (Zemplar®) zeigt positive Effekte auf Herz, Gefäße und Nieren und kann so die Prognose von Dialysepatienten verbessern.

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01 Paricalcitol benefits in Renal disease Induced cardiac MOrbidity study

02 Effects of Paricalcitol capsules on Inflammation and Calcification regulation in CKD stage 5 patients

03 Selective VITamin D receptor activator [paricalcitol] for Albuminuria Lowering study