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Synthesis 2008(10): 1575-1579
DOI: 10.1055/s-2008-1072570
DOI: 10.1055/s-2008-1072570
PAPER
© Georg Thieme Verlag Stuttgart · New York
Efficient Palladium-Catalyzed Synthesis of Aminopyridyl Phosphonates from Bromopyridines and Diethyl Phosphite
Weitere Informationen
Received
15 January 2008
Publikationsdatum:
27. März 2008 (online)
Publikationsverlauf
Publikationsdatum:
27. März 2008 (online)
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Abstract
A general method for coupling aminopyridyl bromides with diethyl phosphite is reported. This efficient route is realized through the use of a palladium catalyst and triethylamine as base.
Key words
palladium - catalysis - phosphonates - cross-coupling - pyridyl halides
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