Synlett 2008(10): 1471-1474  
DOI: 10.1055/s-2008-1078408
LETTER
© Georg Thieme Verlag Stuttgart · New York

A Simple Zinc-Mediated Preparation of Selenols

Claudio Santi*, Stefano Santoro, Lorenzo Testaferri, Marcello Tiecco
Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Via del Liceo 1, 06123 Perugia, Italy
Fax: +39(075)5855116; e-Mail: santi@unipg.it;
Further Information

Publication History

Received 12 March 2008
Publication Date:
16 May 2008 (online)

Abstract

Under acidic conditions zinc reduces diselenides to afford selenols, which can be either isolated or treated in situ with alkyl halides to produce alkyl selenides or with epoxides to give β-hydroxyselenides.