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DOI: 10.1055/s-2008-1079316
© Georg Thieme Verlag Stuttgart · New York
Alternative biologische Therapien - In der Behandlung der Negativsymptomatik und der kognitiven Störungen
Alternative biological treatments - For negative symptoms and cognitive impairmentPublication History
Publication Date:
09 May 2008 (online)
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Die biologische Therapie der Schizophrenie beruht im Wesentlichen auf der Behandlung mit Psychopharmaka. In diesem Beitrag werden zwei weitere, neuere Verfahren vorgestellt, die zukünftig Einfluss auf die Behandlung schizophrener Patienten haben könnten. Die Behandlung mit intensivem körperlichen Training könnte über eine Verbesserung der Neuroplastizität Minussymptome und kognitive Störungen verbessern. Die repetitive transkranielle Magnetstimulation wird heute bereits teilweise zur Behandlung von Minussymptomatik und akustischen Halluzinationen eingesetzt. Für beide Verfahren werden die Rationale und der gegenwärtige Stand der wissenschaftlichen Erkenntnis dargestellt.
The biological therapy of schizophrenia is based on psychopharmacology. In this paper two novel approaches are presented which might contribute to future treatment of patients with schizophrenia. Exercise might improve negative symptoms and cognitive impairment through increased synaptic plasticity. Repetitive transcranial magnet stimulation is already used for the treatment of negative symptoms and acustic hallucinations. For both treatments the rationale and the current state of evidence is reviewed.
Key words
Schizophrenia - exercise - repetitive transcranial magnet stimulation - negative symptoms - cognition - acustic hallucinations
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Korrespondenz
Prof. Dr. med. Frank-Gerald B. Pajonk
Privat-Nerven-Klinik Dr. med. Kurt Fontheim
38704 Liebenburg
Email: pajonk@klinik-dr-fontheim.de