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psychoneuro 2008; 34(4): 201-206
DOI: 10.1055/s-2008-1079316
Schwerpunkt

© Georg Thieme Verlag Stuttgart · New York

Alternative biologische Therapien - In der Behandlung der Negativsymptomatik und der kognitiven Störungen

Alternative biological treatments - For negative symptoms and cognitive impairmentFrank-Gerald Pajonk1 , Peter Flüchter1 , Thomas Wobrock2
  • 1Privat-Nerven-Klinik Dr. med. Kurt Fontheim, Liebenburg(Ärztlicher Leiter: Prof. Dr. F. G. Pajonk)
  • 2Zentrum für Psychosoziale Medizin, Abteilung für Psychiatrie und Psychotherapie, Georg-August-Universität Göttingen(Direktor: Prof. Dr. P. Falkai)
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Publikationsverlauf

Publikationsdatum:
09. Mai 2008 (online)

    Lizenzen und Reprints

Die biologische Therapie der Schizophrenie beruht im Wesentlichen auf der Behandlung mit Psychopharmaka. In diesem Beitrag werden zwei weitere, neuere Verfahren vorgestellt, die zukünftig Einfluss auf die Behandlung schizophrener Patienten haben könnten. Die Behandlung mit intensivem körperlichen Training könnte über eine Verbesserung der Neuroplastizität Minussymptome und kognitive Störungen verbessern. Die repetitive transkranielle Magnetstimulation wird heute bereits teilweise zur Behandlung von Minussymptomatik und akustischen Halluzinationen eingesetzt. Für beide Verfahren werden die Rationale und der gegenwärtige Stand der wissenschaftlichen Erkenntnis dargestellt.

The biological therapy of schizophrenia is based on psychopharmacology. In this paper two novel approaches are presented which might contribute to future treatment of patients with schizophrenia. Exercise might improve negative symptoms and cognitive impairment through increased synaptic plasticity. Repetitive transcranial magnet stimulation is already used for the treatment of negative symptoms and acustic hallucinations. For both treatments the rationale and the current state of evidence is reviewed.

Key words

Schizophrenia - exercise - repetitive transcranial magnet stimulation - negative symptoms - cognition - acustic hallucinations

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Korrespondenz

Prof. Dr. med. Frank-Gerald B. Pajonk

Privat-Nerven-Klinik Dr. med. Kurt Fontheim

38704 Liebenburg

eMail: pajonk@klinik-dr-fontheim.de