Multiplate whole blood impedance aggregometry: A recent experience

Jaimie Breugelmans; Francine Vertessen; Gerhard Mertens; Alain Gadisseur; Marc Van der Planken

doi:10.1160/TH08-07-0438

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2008; 100(04): 725-726
DOI: 10.1160/TH08-07-0438

Letters to the Editor

Schattauer GmbH

Multiplate whole blood impedance aggregometry: A recent experience

Authors

Jaimie Breugelmans

¹Laboratory of Hematology & Hemostasis, Antwerp University Hospital, Edegem, Belgium
Francine Vertessen

¹Laboratory of Hematology & Hemostasis, Antwerp University Hospital, Edegem, Belgium

²Hemostasis Unit, Antwerp University Hospital, Edegem, Belgium
Gerhard Mertens

¹Laboratory of Hematology & Hemostasis, Antwerp University Hospital, Edegem, Belgium
Alain Gadisseur

²Hemostasis Unit, Antwerp University Hospital, Edegem, Belgium
Marc Van der Planken

¹Laboratory of Hematology & Hemostasis, Antwerp University Hospital, Edegem, Belgium

²Hemostasis Unit, Antwerp University Hospital, Edegem, Belgium

Abstract

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References

References
1 Johnson A, Dovlatova N, Heptinstall S. Multiple electrode aggregometry and P2Y₁₂ antagonists. Thromb Haemost 2008; 99: 1127-1129.
2 Neubauer H, Lask S, Engelhardt A. et al. How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification. Thromb Haemost 2008; 99: 357-362.
3 Tóth O, Calatzis A, Penz S. et al. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost 2006; 96: 781-788.
4 Mueller T, Dieplinger B, Poelz W. et al. Utility of whole blood impedance aggregometry for the assessment of clopidogrel action using the novel Multiplate analyzer-comparison with two flow cytometric methods. Thromb Res 2007; 121: 249-258.
5 Dyszkiewicz-Korpanty A, Olteanu H, Frenkel EP. et al. Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100). Platelets 2007; 18: 491-496.
6 Perneby C, Wallén NH, Hofman-Bang C. et al. Effect of clopidogrel treatment on stress-induced platelet activation and myocardial ischemia in aspirin-treated patients with stable coronary artery disease. Thromb Haemost 2007; 98: 1316-1322.
7 Sibbing D, Braun S, Jawansky S. et al. Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment. Thromb Haemost 2008; 99: 121-126.
8 Dynabyte Informationssysteme GmbH, Homepage. http://www.multiplate.net Accessed on July, 5, 2008
9 Fox SC, Behan MW, Heptinstall S. Inhibition of ADP-induced intracellular Ca2+ responses and platelet aggregation by the P2Y12 receptor antagonists AR-C69931MX and clopidogrel is enhanced by prostaglandin E1. Cell Calcium 2004; 35: 39-46.
10 Siller-Matula J, Schrör K, Wojta J. et al. Thienopyridines in cardiovascular disease: focus on clopidogrel resistance. Thromb Haemost 2007; 97: 385-393.
11 Angiolillo DJ, Fernandez-Ortiz A, Bernardo E. et al. Variability in individual responsiveness to clopidogrel. Clinical implications, management, and future perspectives. J Am Coll Cardiol 2007; 49: 1505-1516.