Thromb Haemost 2012; 107(05): 827-837
DOI: 10.1160/TH11-09-0611
Review Article
Schattauer GmbH

Infections and inflammatory diseases as risk factors for venous thrombosis

A systematic review
Y. I. G. Vladimir Tichelaar
1   Department of Hematology, Division of Hemostasis and Thrombosis, University Medical Center Groningen, Groningen, the Netherlands
,
Hanneke J. C. Kluin-Nelemans
1   Department of Hematology, Division of Hemostasis and Thrombosis, University Medical Center Groningen, Groningen, the Netherlands
,
Karina Meijer
1   Department of Hematology, Division of Hemostasis and Thrombosis, University Medical Center Groningen, Groningen, the Netherlands
› Author Affiliations
Further Information

Publication History

Received: 06 September 2011

Accepted after major revision: 24 January 2012

Publication Date:
25 November 2017 (online)

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Summary

Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical epidemiological studies have focussed on inflammatory or infectious diseases as risk factors for venous thrombosis. Although a few reviews and many case reports or studies on these topic has been written, a review reporting relative or absolute risks for venous thrombosis has not been published yet. We performed a systematic review using Medline, Pubmed and Embase and found 31 eligible articles. Inflammatory bowel disease, ANCA-associated vasculitis, infections in general and more specifically, human immunodeficiency virus, pneumonia and urinary tract infections are associated with an increased risk of venous thrombosis.