Oncogenic transformation is closely linked to coagulation activation and cancer-associated
venous thromboembolism (VTE) is a common problem. Guidelines recommend thromboprophylaxis
with a low molecular weight heparin for hospitalized cancer patients. However, thromboprophylaxis
is not customarily advised for ambulatory cancer patients. Cancer patients with VTE
are usually treated with a low molecular weight heparin for 3–6 months. Vitamin K
antagonists have a higher bleeding risk and there are not sufficient data to recommend
any of the new oral anticoagulants. All physicians taking care of cancer patients
should be aware of the current guideline recommendations. Oncology professionals should
educate patients about the signs of VTE.
Keywords
Cancer - venous thromboembolism - guidelines - tumour - prophylaxis