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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2017; 75(01): 3-8
DOI: 10.1590/0004-282X20160173
Article

No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

Não foi observada correlação entre os níveis séricos de vitamina D e a incapacidade em pacientes com esclerose múltipla entre as latitudes Sul 18° e 30°
Yara Dadalti Fragoso
1   Universidade Metropolitana de Santos, Departamento de Neurologia, Santos SP, Brasil
,
Tarso Adoni
2   Hospital Sírio Libanes, Departamento de Neurologia, São Paulo, SP, Brasil
,
Soniza Vieira Alves-Leon
3   Universidade Federal do Rio de Janeiro, Departamento de Neurologia, Rio de Janeiro RJ, Brasil
,
Samira L. Apostolos-Pereira
4   Universidade de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil
,
Walter Oleschko Arruda
5   Universidade Federal do Paraná, Departamento de Neurologia, Curitiba PR, Brasil
,
Joseph B. Bidin Brooks
1   Universidade Metropolitana de Santos, Departamento de Neurologia, Santos SP, Brasil
,
Henrique S. Rodrigues Cal
6   Departamento de Neurologia, Universidade Federal Fluminense, Niterói RJ, Brasil
,
Carlos A. Albuquerque Damasceno
7   Universidade Federal de Juiz de Fora, Departamento de Neurologia, Juiz de Fora MG, Brasil
,
Paulo Diniz Gama
8   Pontifícia Universidade Católica, Departamento de Neurologia, Sorocaba SP, Brasil
,
Marcus V. Magno Goncalves
9   Centro Hospitalar Unimed, Departamento de Neurologia, Joinville SC, Brasil
,
Carlos A. da Silva de Jesus
10   Universidade Federal de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil
,
Suzana C. Nunes Machado
11   Hospital de Caridade, Departamento de Neurologia, Florianópolis SC, Brasil
,
Letícia Fezer Mansur
3   Universidade Federal do Rio de Janeiro, Departamento de Neurologia, Rio de Janeiro RJ, Brasil
,
Andre P. da Cunha Matta
6   Departamento de Neurologia, Universidade Federal Fluminense, Niterói RJ, Brasil
,
Maria Fernanda Mendes
12   Clínica Neurológica São Paulo, Departamento de Neurologia, São Paulo SP, Brasil
,
Rogerio Rizo Morales
13   Universidade Federal de Uberlândia, Departamento de Neurologia, Uberlândia MG, Brasil
,
Adaucto Wanderley da Nobrega Jr
11   Hospital de Caridade, Departamento de Neurologia, Florianópolis SC, Brasil
,
Monica K. Fiuza Parolin
14   Clínica Neurológica Curitiba, Departamento de Neurologia, Curitiba PR, Brasil
,
Mario Pietro Peres
10   Universidade Federal de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil
,
Marlise de Castro Ribeiro
15   Universidade Federal de Ciências da Saúde de Porto Alegre, Departamento de Neurologia, Porto Alegre RS, Brasil
,
Heloisa Helena Ruocco
16   Universidade de Jundiaí, Departamento de Neurologia, Jundiaí SP, Brasil
,
Simone Scherpenhuijzen
3   Universidade Federal do Rio de Janeiro, Departamento de Neurologia, Rio de Janeiro RJ, Brasil
,
Fabio Siquinelli
17   Universidade Regional de Blumenau, Departamento de Neurologia, Blumenau SC, Brasil
,
Patrick N. Stoney
18   University of Aberdeen, Institute of Medical Sciences, Scotland, United Kingdom
,
Daniel Lima Varela
19   Serviço de Neurologia e Neurocirurgia de Passo Fundo, Departamento de Neurologia, Passo Fundo RS, Brasil
,
Audred Cristina Biondo Eboni
9   Centro Hospitalar Unimed, Departamento de Neurologia, Joinville SC, Brasil
,
Caroline Vieira Spessotto
1   Universidade Metropolitana de Santos, Departamento de Neurologia, Santos SP, Brasil
,
Elisa Teixeira da Rocha
7   Universidade Federal de Juiz de Fora, Departamento de Neurologia, Juiz de Fora MG, Brasil
,
Pamela Emanuele Lacerda
7   Universidade Federal de Juiz de Fora, Departamento de Neurologia, Juiz de Fora MG, Brasil
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ABSTRACT

Objective:

Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area.

Methods:

Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn.

Results:

The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration.

Conclusion:

At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.

RESUMO

Objetivo:

Vitamina D assumiu um papel central na pesquisa e tratamento da esclerose múltipla (EM). O objetivo deste estudo foi avaliar os níveis séricos de vitamina D de pacientes com EM e controles que residem em uma área tropical.

Métodos:

Foram analisados dados de 535 pacientes com EM e 350 indivíduos controle em 14 cidades próximas ao Trópico de Capricórnio.

Resultados:

O valor médio da determinação de 25-OH vitamina D foi 26,07 ± 10,27 ng/mL para controles e 28,03 ± 12,19 ng/mL para pacientes com EM. Não houve correlação entre os níveis de vitamina D e o grau de incapacidade ao longo da duração da doença.

Conclusão:

Pelo menos na região que cerca o Trópico de Capricórnio, os níveis séricos de vitamina D estão entre valores de 20 a 30 ng/mL tanto para controles quanto para pacientes com EM.

Keywords:

vitamin D - multiple sclerosis - latitude

Palavras-chave:

vitamina D - esclerose múltipla - latitude


Publication History

Received: 07 August 2016

Accepted: 09 August 2016

Article published online:
06 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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