Guideline for multiple sclerosis treatment in Brazil: Consensus from the Neuroimmunology Scientific Department of the Brazilian Academy of Neurology

Elizabeth Regina Comini-Frota; Cláudia C. F. Vasconcelos; Maria Fernanda Mendes

doi:10.1590/0004-282X20160185

Arquivos de Neuro-Psiquiatria, Table of Contents

CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2017; 75(01): 57-65
DOI: 10.1590/0004-282X20160185

Guidelines

Guideline for multiple sclerosis treatment in Brazil: Consensus from the Neuroimmunology Scientific Department of the Brazilian Academy of Neurology

Orientações para tratamento da esclerose múltipla no Brasil: Consenso do Departamento Científico de Neuroimunologia da Academia Brasileira de Neurologia

Elizabeth Regina Comini-Frota

¹Universidade José do Rosário Vellano, UNIFENAS, Belo Horizonte MG, Brasil

⁴Academia Brasileira de Neurologia, Departamento Científico de Neuroimunologia (DCNI), São Paulo SP, Brasil

,

Cláudia C. F. Vasconcelos

²Universidade Federal do Estado do Rio de Janeiro, Departamento de Neurologia, Rio de Janeiro RJ, Brasil

⁴Academia Brasileira de Neurologia, Departamento Científico de Neuroimunologia (DCNI), São Paulo SP, Brasil

,

Maria Fernanda Mendes

³Santa Casa de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil

⁴Academia Brasileira de Neurologia, Departamento Científico de Neuroimunologia (DCNI), São Paulo SP, Brasil

› Author Affiliations

Abstract

ABSTRACT

Multiple sclerosis has become an ever-increasing challenge to neurologists. With the release of the latest medications on the market, Brazilian neurologists feel divided between following their patients’ evolution in accordance with the strict rules established by the Brazilian Ministry of Health regarding drug distribution, or following disease progression and worsening in accordance with the evidence in the literature. Therefore, a systematic review of the main published treatment guidelines was conducted and an escalating therapy proposed for guiding multiple sclerosis patient treatment in Brazil.

RESUMO

A esclerose múltipla vem se tornando um desafio crescente para os neurologistas. Com o lançamento de novos medicamentos no mercado, os neurologistas brasileiros se encontram divididos entre, apesar da evolução dos seus pacientes, seguir as regras restritas estabelecidas pelo Ministério da Saúde para distribuição de medicamentos, ou ao contrário, considerar a progressão e piora da doença, em concordância com as evidências da literatura. Devido a este impasse foi realizada uma revisão sistemática sobre as principais orientações de tratamento publicadas e foi proposto um escalonamento terapêutico para orientar o tratamento dos pacientes com esclerose múltipla no Brasil.

Keywords:

multiple sclerosis - Consensus - treatment

Palavras-chave:

esclerose múltipla - Consenso - tratamento

Full Text

References

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