CC BY-NC-ND 4.0 · Ibnosina Journal of Medicine and Biomedical Sciences 2014; 06(03): 125-129
DOI: 10.4103/1947-489X.210373
Article

Histological effects of permethrin insecticide on the testis of adult wistar rats

Gabriel Omotoso
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, PMB 1515, Ilorin, 240003, Nigeria
,
Ismail Onanuga
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, PMB 1515, Ilorin, 240003, Nigeria
,
Ridwan Ibrahim
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, PMB 1515, Ilorin, 240003, Nigeria
› Author Affiliations

Permethrin is a common constituent in some household insecticides. This study examined the effects of this chemical on the testicular histology of exposed rats. Fifteen adult male Wistar rats were subgrouped into a control and two treatment groups. The controls were fed on normal rat feeds, whilst the diet of animals in the two treatment groups was mixed with 500 mg/kg and 1000 mg/kg Permethrin respectively. An increase in body weights and organ weights was observed in the animals in both treatment groups. Various degrees of histological alterations in the structure of their seminiferous tubules were also observed in comparison with the control group. These abnormalities included disruption of the normal architecture, reduction in the population of mature sperm cells, wider luminal diameter and reduced interstitial spaces. These effects could impair the fertility potential of male subjects.



Publication History

Received: 03 September 2013

Accepted: 05 January 2014

Article published online:
07 July 2022

© 2014. The Libyan Authority of Scientific Research and Technologyand the Libyan Biotechnology Research Center. All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License,permitting copying and reproductionso long as the original work is given appropriate credit. Contents may not be used for commercial purposes, oradapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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