ABSTRACT
Objective: Chronic periodontitis (CP) is a common inflammatory disease that causes destruction
to the supporting tissues of the teeth. Many treatment modalities tried to stop the
disease progression. Platelet-rich plasma (PRP) is one of the regenerative methods
that used in adjunct to conventional periodontal treatment. The aim of this study
was to evaluate the anti-inflammatory effect of PRP by monitoring the lymphocyte count
before and after its application to the periodontal pocket. Materials and Methods: Twenty patients, with CP and a pocket depth equal to or deeper than 4 mm, subjected
to scaling, root planing, and PRP injection into the pocket. The lymphocyte count
measured before and after 1 month from PRP application. Clinical periodontal parameters
were taken during two visits (1 month apart), with customized stent fabrication. Results: All clinical periodontal parameters showed a reduction in their value following
1 month of PRP application. . There was a noticeable reduction in lymphocyte count
from (mean 2.47 ± 0.91) to (mean 1.94 ± 0.77). Conclusion: In addition to its traditional uses, PRP has a great role in the periodontal treatment
by its anti-inflammatory effect.
Key words:
Lymphocyte count - periodontal pocket - platelet-rich plasma