Abstracts (HTML) List of Authors

Kabbani, Mohammad

ABHD5 overexpression protects PNPLA3-148M primary human hepatocytes from steatosis in liver chimeric mice with NAFLD

Kabelitz, Martin Andreas

Combining clinical data and systemic inflammation to predict the outcome after TIPS: An AI-based approach

Kacprowski, Tim

Inflammatory milieu alterations associated with carcinogenesis persist in cirrhotic patients despite HCV cure

Kadioglu, Amine

Auswirkungen des Alkoholkonsums auf den Leberphänotyp von Personen mit Alpha1-Antitrypsin-Mangel

Kakoschky, Bianca

Tumour-specific activation of a tumour-blood transport that may improve the diagnostic accuracy of blood tumour markers

Kalff, Jörg

Renal impairment after liver transplant is associated with indication and stabilises 1 year after transplant

Kalil, Jennifer

Rapid liver regeneration following PVE/HVE improves overall survival compared to PVE alone – A midterm analysis of the multicenter DRAGON 0 cohort

Kalinowski, Piotr

Genetic variant in the hepatobiliary cholesterol transporter is associated with increased gallstone risk in the obese and with gallbladder cancer in general population

Kallenbach, Michael

Role of hypersplenism and transjugular intrahepatic portosystemic shunt implantation on cytopenia in decompensated liver cirrhosis

Kalweit, Emma

Characterizing Molecular Pathways of Precancerous Changes in Hepatocytes Under Metabolic Overload

Kandulski, Arne

Überlebensdatenanalyse von Patienten mit hepatozellulären Karzinoms (HCC) unter First-Line Therapie mit Atezolizumab/Bevacizumab (AB) in Abhängigkeit der Leberfunktion – Analyse über 4 Jahre (01/2019–03/2023) eines universitären Zentrums
Patients with primary sclerosing cholangitis exhibit a specific metabolomic and lipidomic profile
Non-invasive high throughput monitoring of exon-specific p53 isoform expression identifies new promising therapeutics for cancer patients with altered p53 status

Kang, Grace

Insufficient control of cholestatic pruritus in primary biliary cholangitis (PBC) with current therapies: preliminary baseline data from the ongoing Phase 3 GLISTEN study

Kaps, Leonard

Cancer-associated fibroblasts specific gene silencing for anti-stromal therapy in primary liver cancer using novel anti-MFAP-5 siRNA-loaded polymeric nanoparticles
The effect of methylglyoxal and glyoxalase-1 metabolism on immune-mediated signaling and overall survival in biliary tract cancer

Karim, Majedul

Carbohydrate response element binding protein (ChREBP) correlation and contribution to NAFLD-mediated hepatocarcinogenesis

Karl, Anna

Serum proteomic signature of alcohol detoxification and the role of PNPLA3 genotype

Karpen, Saul J.

Kidney specific deficiency of the Ileal Bile Acid Transporter is hepatoprotective in a murine model of cholestatic liver disease

Kather, Jakob Nikolas

Machine learning for liver cancer risk stratification on population-level data

Katrin, Lisa Katrin

Prognostic significance of platelet count in HCC patients adjusted for surrogate parameters of portal hypertension

Katzer, Katrin

Fatty liver diseases are more common in post-COVID-syndrome

Kaya, Eda

Deciphering the implications of the MAFLD and MASLD definitions in the NAFLD population: Results from a single-center biopsy study
Analytical methods used in creatinine measurement significantly impact Model for End Stage Liver Disease score: Is there a need for modification?

Keimburg, Simone A.

Transjugular intrahepatic portosystemic shunt improves Quality of Life in patients with cirrhosis

Keitel-Anselmino, Verena

Impaired transitioning from an inactive to an active state of FXR underlies a PFIC5 phenotype
Patient-specific hepatobiliary organoids elucidate functional alterations in intrahepatic cholestasis
First description of a genetic variant in Semaphorin 7A in a case of intrahepatic cholestasis of pregnancy
Characterization of the cellular expression pattern of bile acid receptors in intrahepatic cholangiocellular carcinoma
The impact of activated MAIT-cells on cholestatic liver diseases

Kelsch, Lara

Antibodies to food antigens contribute to hypergammaglobulinemia in patients with decompensated liver cirrhosis
The decrease of HCV-specific neutralizing antibody responses after DAA therapy is associated with weak envelope-specific CD4 T cell immunity

Kemming, Janine

Unique phenotype of CD8+T Cell Responses in Acute Hepatitis C Virus Infections

Kempa, Sally

Patients with primary sclerosing cholangitis exhibit a specific metabolomic and lipidomic profile

Kendrick, Stuart

Pegylated interferon reduces relapses following bepirovirsen treatment in participants with chronic hepatitis B virus infection on nucleos(t)ide analogues: end of study results from the Phase 2b B-Together study
Evidence of durable response to bepirovirsen in B-Clear responders: B-Sure first annual report

Khanal, Rajendra

Regulation of SARS-CoV-2 infection by microRNAs in primary human hepatocytes

Kießling, Paul

Multimodal and site-specific differentiation trajectories of cDC2 in liver damage and cholestasis

Killer, Alexander

‘Accidental functional cure’: HBsAg loss in a HBV/HDV/HIV-coinfected patient upon non-adherence to treatment with nucleos(t)ide-analogues

Killmer, Saskia

Imaging Mass Cytometry as a method for improved diagnostics in patients with CUP syndrome and primary manifestation in the liver

Kimmann, Markus

Ultraschall-definierte Sarkopenie ist ein unabhängiger Prädiktor für akute Dekompensation und ACLF bei chronischer Lebererkrankung
Automated assessment of three-dimensional TIPS geometry predicts shunt dysfunction in decompensated liver cirrhosis
Transjugular Intrahepatic Portosystemic Shunt improves rebleeding and survival in gastric variceal hemorrhage

Klein, Isabel Madeleine

Regulation of SARS-CoV-2 infection by microRNAs in primary human hepatocytes

Klein, Sabine

Effects of rifaximin-α on liver phenotype in murine models of early stage alcohol-associated and metabolic-dysfunction associated steatotic liver disease

Kleine, Moritz

Transcriptional profiling of tumor-specific CD8 T-cells shows contribution of TIGIT to T-cell exhaustion in liver cancer

Klein-Scory, Susanne

Characterizing Molecular Pathways of Precancerous Changes in Hepatocytes Under Metabolic Overload

Klindt, Caroline

Kidney specific deficiency of the Ileal Bile Acid Transporter is hepatoprotective in a murine model of cholestatic liver disease

Klockner, Roman

The Freiburg Index of Post-TIPS Survival (FIPS) identifies patients with further decompensation after transjugular intrahepatic portosystemic shunt implantation: a multicenter observational study

Klöhn, Mara

Propagation of hepatitis E virus in human neuronal cells as infection model system for extrahepatic manifestations
Evolution of resistance-associated variants in HEV-patients with sofosbuvir mono- or sofosbuvir-ribavirin combinatory therapy

Kluwe, Johannes

The Freiburg Index of Post-TIPS Survival (FIPS) identifies patients with further decompensation after transjugular intrahepatic portosystemic shunt implantation: a multicenter observational study

Knedla, Lukas

Pharmaceutical inhibition of JNK/c-Jun-signalling in S. mansoni-infected mice aggravated liver damage

Knodel, Markus M.

Intracellular “in silico microscopes” – fully 3D spatial Hepatitis C virus replication model simulations

Knolle, Percy A.

A tissue-rheostat induced by hepatic cells limits antiviral CD8 T cell immunity during persistent infections
Liver immunity index: predicting immune control of chronic hepatitis B from circulating CD8 T cells
Unleashing Synergistic T Cell Power: Novel Insights into Cooperative Killing of Virus-Infected Hepatocytes by Conventional and Auto-Aggressive CD8 T Cells
Molecular pathways defining human CD8 T cell auto-aggression in autoimmune liver diseases

Knudsen, Arne

KAIGI HCC – transsektorale Austauschplattform zur Therapie des HCC

Koch, Chiara

An innovative interprofessional approach to therapeutic drug monitoring in liver failure improves guideline adherence and quality of care

Koelfat, Kiran V.K.

Partial liver resection alters the bile salt-FGF19 axis in patients with perihilar cholangiocarcinoma: implications for liver regeneration

Koenecke, Christian

Accumulation of regulatory T cells correlate with severity of NASH in patients and mice

Koerkamp, Bas Groot

Oxaliplatin-induced spleen hypertrophy as a predictor of liver-specific complications following curative resection of colorectal liver metastases.
A comparison of clinical risk scores for survival prediction after curative-intent resection of colorectal liver metastases.

Köhler, Bruno

Oncogene-induced long non-coding RNA (lncRNA) signatures in liver cancer
Screening for putative actionable targets reveals changes in PD-L1 expression pattern throughout biliary carcinogenesis

Köhler, Michael

The Freiburg Index of Post-TIPS Survival (FIPS) identifies patients with further decompensation after transjugular intrahepatic portosystemic shunt implantation: a multicenter observational study
Transjugular Intrahepatic Portosystemic Shunt improves rebleeding and survival in gastric variceal hemorrhage

Kohnke-Ertel, Birgit

Influence of CD44 on cell proliferation and fibrosis in Mdr2-/- mice

Köhrer, Karl

Progression of MASLD goes along with significant changes of a recruited and TGFb sensitive macrophage population

Kojic, Sabrina

The role of the pancreatic polypeptide-neuropeptide Y receptor 4-axis in hepatocellular carcinoma progression

Koliogiannis, Dionysios

Implications of peak-MELD-scores for the outcome of patients listed for liver transplantation
The outcome after liver transplantation may be affected by the circadian rhythm of liver transplant donors

Komori, Atsumasa

Pegylated interferon reduces relapses following bepirovirsen treatment in participants with chronic hepatitis B virus infection on nucleos(t)ide analogues: end of study results from the Phase 2b B-Together study

Komura, Takuya

Evidence of durable response to bepirovirsen in B-Clear responders: B-Sure first annual report

Kondylis, Evangelos

Proliferative and Metabolic Reprogramming by the Lysine-Specific Demethylase 1 in Hepatocellular Carcinoma
A Mavs-induced type I IFN pathway contributes to non-viral liver injury upon hepatic autophagy impairment
Dissecting cell death and NF-kB in TAK1-deficient livers

Konstantis, Georgios

Safety of coronary angiography in patients with cirrhosis as part of an evaluation for liver transplantation

Koop, Paul

Machine learning for liver cancer risk stratification on population-level data

Koop, Paul-Henry

Metabolic Phenotype and Morbidity in Patients with Primary Biliary Cholangitis

Koppe, Christiane

Deciphering the role of ferroptosis in non alcoholic fatty liver disease

Korenblik, Remon

Portal and Hepatic Vein Embolization in Perihilar Cholangiocarcinoma – Insights from the DRAGON and EuroLVD Registries
Results of the prospective international multicenter DRAGON 1 trial investigating combined portal and hepatic vein embolization in patients with colorectal liver metastases and small future liver remnants
Rapid liver regeneration following PVE/HVE improves overall survival compared to PVE alone – A midterm analysis of the multicenter DRAGON 0 cohort

Kosinska, Anna D.

Liver immunity index: predicting immune control of chronic hepatitis B from circulating CD8 T cells

Kraemer, Benjamin

Genetic variation in angiotensin II type 1 receptor is linked to lipid levels and hepatic steatosis in alcohol-associated liver disease, but not to complications of liver disease

Kraft, Anke

Role of a G-CSF/IL-13 Ratio and Cytokine Dynamics in ALT Flares
Enhancing HBV-Specific T Cell Responses through Epigenetic Modulation and Immune Checkpoint Inhibition in Chronic HBV Infection
CXCR6+PD1+CD8 T Cells: Key Markers of Liver Inflammation and Dysfunction in ALT Flares
Inflammatory milieu alterations associated with carcinogenesis persist in cirrhotic patients despite HCV cure
The Yin and Yang of γδ T cells in hepatitis B virus (HBV) infection
Unique features of a cytotoxic, protective CD8+T-cell population in chronic HBV infection
HLA class I-associated mutations are predominantly located in the HBV core protein and restricted to HBeAg-negative HBV infection

Krag, Aleksander

Auswirkungen des Alkoholkonsums auf den Leberphänotyp von Personen mit Alpha1-Antitrypsin-Mangel
Factors associated with the development of liver-related endpoints in adults with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype)
Metabolische Veränderungen und deren Zusammenhang mit dem Leberphänotyp bei Erwachsenen mit homozygotem Alpha1-Antitrypsin-Mangel (Pi*ZZ-Genotyp)
Effects of rifaximin-α on liver phenotype in murine models of early stage alcohol-associated and metabolic-dysfunction associated steatotic liver disease

Kratzer, Alexander

An innovative interprofessional approach to therapeutic drug monitoring in liver failure improves guideline adherence and quality of care

Kraus, Nico

Higher prevalences and titers of CMV, EBV and HSV1 viremia in patients with acute-on-chronic liver failure derived from the ACLF-I cohort

Krause, Jenny

Testosterone as modulator of immune responses in female hepatic autoimmunity

Krawczyk, Marcin

PNPLA3 fatty liver risk allele was fixed in Neanderthals and segregates neutrally in humans
Genetic variant in the hepatobiliary cholesterol transporter is associated with increased gallstone risk in the obese and with gallbladder cancer in general population

Krawczyk, Marek

Genetic variant in the hepatobiliary cholesterol transporter is associated with increased gallstone risk in the obese and with gallbladder cancer in general population

Krizanac, Marinela

Reciprocal Inhibitory Regulation of TGF-β1 Signaling and Cholesterol Metabolism in Hepatocytes

Kruk, Beata

Genetic variant in the hepatobiliary cholesterol transporter is associated with increased gallstone risk in the obese and with gallbladder cancer in general population

Krupa, Lukasz

Genetic variant in the hepatobiliary cholesterol transporter is associated with increased gallstone risk in the obese and with gallbladder cancer in general population

Kubes, Paul

Sustained macrophage alterations during chronic injury regression beget increased susceptibility to infections

Kubitza, Marion

Phosphorylation of α-and ß-catenin by ALR through EGF-Receptor dependent mechanisms may results in disruption of cell-cells contacts
IL-6 receptor availability and IL-6/STAT3 signal transduction is regulated by ALR through altered sheddase ADAM17

Küchle, Merlin

Cholestatic Hepatitis as a Rare Manifestation of Infectious Mononucleosis
Turmeric-induced acute liver failure – A case report of an idiosyncratic drug-induced liver injury (DILI)
Liver transplantation in a 64-year-old male patient with end stage liver disease due to langerhans cell histiocytosis

Kühnel, Florian

Interfering with ß-catenin-induced immunosuppression in HCC by cytokine-armed virotherapy
Expression of target-independent membrane-associated T-cell engagers (MATEs) provides oncolytic adenoviruses with effective T-cell activation capabilities and unrestrained applicability
Development of a model to analyze the relevance of MHC class II epitopes for hepatocellular carcinoma immunity
Transcriptional profiling of tumor-specific CD8 T-cells shows contribution of TIGIT to T-cell exhaustion in liver cancer

Kulle, Elexandra E.

Testosterone as modulator of immune responses in female hepatic autoimmunity

Kumar, Pavitra

Unsaturated fatty acids aggravate mitochondrial dysfunction in senescent primary hepatocytes

Kumthekar, Aditi

Identification of blood based biomarkers for hepatocellular carcinoma screening

Kunst, Claudia

Liver injury in malaria: from mild hepatitis to fulminant liver failure
Patients with primary sclerosing cholangitis exhibit a specific metabolomic and lipidomic profile
Paraptosis – a new bacteria-induced cell death in intestinal epithelial cells and its role in the development of spontaneous bacterial peritonitis
Inhibition of bacterial proteases prevents E-Cadherin cleavage in intestinal epithelial cells observed in spontaneous bacterial peritonitis
The role of p53 and its isoforms in spontaneous bacterial peritonitis
Development of a 3D Intestinal Cell Culture System to Explore the Underlying Mechanisms of Spontaneous Bacterial Peritonitis (SBP)
Non-invasive high throughput monitoring of exon-specific p53 isoform expression identifies new promising therapeutics for cancer patients with altered p53 status

Kunstein, Anselm

Soluble urokinase plasminogen activator receptor (suPAR) levels predict survival in patients with portal hypertension undergoing TIPS
Lactate metabolism in decompensated liver cirrhosis
Role of hypersplenism and transjugular intrahepatic portosystemic shunt implantation on cytopenia in decompensated liver cirrhosis

Kupke, Paul

Cytokine response of natural killer cells to hepatitis B virus infection depends on monocyte co-stimulation

Kuppe, Christoph

Multimodal and site-specific differentiation trajectories of cDC2 in liver damage and cholestasis

Kurosaki, Masayuki

Evidence of durable response to bepirovirsen in B-Clear responders: B-Sure first annual report

Küsgens, Lena

Dissecting cell death and NF-kB in TAK1-deficient livers

Kweon, Youngoh

Evidence of durable response to bepirovirsen in B-Clear responders: B-Sure first annual report