Widmung
Herrn Prof. Dr. G. A. Müller, Direktor Nephrologie/Rheumatologie Uni-Klinik Göttingen
gewidmet für viele Jahre der auch persönlich ausgezeichneten Zusammenarbeit unserer
Kliniken in Forschung und Lehre.
Abstract
Following the publication of the new US guidelines, especially the new classifications
of hypertension and the general reduction in treatment targets were discussed worldwide.
Applying the US guidelines to a recent German cohort study would in practice lead
to a significant increase in the diagnosis of “hypertension” in untreated patients.
The number of under-adjusted patients would also increase sharply, increasing more
than those predicted in the US Guidelines. Affected by an intensified antihypertensive
therapy would be particularly elderly patients, in which adverse drug reactions but
also occur more frequently. It seems doubtful whether the massive increase in the
diagnosis “hypertension” can improve the supply situation: the opposite effect of
avoiding therapists and patients could occur. Determining the individual risk with
suitable, evaluated instruments certainly makes sense to treat more targeted patients.
More important than new blood pressure limits is a more accurate classification of
blood pressure. Repeated self-measurements and ambulatory blood pressure measurement
lead to a better selection of patients benefiting from a therapy.
Die amerikanischen Fachgesellschaften AHA und ACC haben im November 2017 ihre Hypertonie-Leitlinien
ausführlich überarbeitet und aktualisiert. Setzt man die neuen Grenzwerte und Zielblutdruckwerte
aber um, wie würde sich dann die Zahl der neu bzw. intensiver zu behandelnden Patienten
hierzulande verändern? Am Beispiel einer aktuell laufenden Kohortenstudie im Nordwesten
Deutschlands (ELITE) wurde dieser Frage nachgegangen.
Schlüsselwörter
Hypertonie-Leitlinien - ELITE-Studie - Prävalenz - antihypertensive Therapie
Key words
hypertension guidelines - ELITE study - prevalence - antihypertensive therapy