Adaption an subletale Wirkstoffkonzentrationen – Beispiel Benzalkoniumchlorid

Benzalkoniumchlorid kommt als biozider Wirkstoff in verschiedenen Desinfektionsmitteln in direkter Patientenumgebung zum Einsatz – v. a. zur Flächendesinfektion, aber auch in Hautantiseptika. Subletale Konzentrationen können jedoch zahlreiche Bakterienspezies unempfindlich machen, auch gegenüber anderen Wirkstoffen oder Antibiotika! Deshalb sollte es nur dann Verwendung finden, wenn es einen nachgewiesenen Nutzen für den Patienten hat.

Schlüsselwörter

Benzalkoniumchlorid - subletale Konzentration - Toleranz - Resistenz - Antiseptic Stewardship

Key words

benzalkonium chloride - sublethal concentration - tolerance - resistance - antiseptic stewardship

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