Diabetic Pulmopathy: A New Clinical Challenge for Diabetology

Stefan Kopf; Peter P. Nawroth

doi:10.1055/a-0715-2743

Experimental and Clinical Endocrinology & Diabetes, Table of Contents

Exp Clin Endocrinol Diabetes 2018; 126(09): 590-591
DOI: 10.1055/a-0715-2743

Commentary

Diabetic Pulmopathy: A New Clinical Challenge for Diabetology

Authors

Stefan Kopf

¹University Hospital of Heidelberg, Department of Endocrinology, Diabetology and Clinical Chemistry (Internal Medicine I), Heidelberg, Germany

²German Center of Diabetes Research (DZD), associated Partner in the DZD; München-Neuherberg, Germany
Peter P. Nawroth

¹University Hospital of Heidelberg, Department of Endocrinology, Diabetology and Clinical Chemistry (Internal Medicine I), Heidelberg, Germany

²German Center of Diabetes Research (DZD), associated Partner in the DZD; München-Neuherberg, Germany

³Joint-IDC, Institute for Diabetes and Cancer at Helmholtz Zentrum Munich and University of Heidelberg, Germany

Abstract

Full Text

References

References
1 Kopf S, Groener JB, Kender Z. et al. Breathlessness and restrictive lung disease: An important diabetes-related feature in patients with type 2 diabetes. Respiration 2018; 96: 29-40
2 Berliner D, Schneider N, Welte T. et al. The differential diagnosis of dyspnea. Deutsches Arzteblatt International 2016; 113: 834-845
3 Kreuter M, Ehlers-Tenenbaum S, Palmowski K. et al. Impact of comorbidities on mortality in patients with idiopathic pulmonary fibrosis. PloS One 2016; 11: e0151425
4 Kim YJ, Park JW, Kyung SY. et al. Clinical characteristics of idiopathic pulmonary fibrosis patients with diabetes mellitus: The national survey in Korea from 2003 to 2007. J Korean Med Sci 2012; 27 : 756-760
5 Kishaba T, Nagano H, Nei Y. et al. Clinical characteristics of idiopathic pulmonary fibrosis patients according to their smoking status. J Thorac Dis 2016; 8: 1112-1120
6 Sosulski ML, Gongora R, Danchuk S. et al. Deregulation of selective autophagy during aging and pulmonary fibrosis: The role of TGFbeta1. Aging Cell 2015; 14: 774-783
7 Sinha K, Das J, Pal PB. et al. Oxidative stress: The mitochondria-dependent and mitochondria-independent pathways of apoptosis. ArchToxicol 2013; 87: 1157-1180
8 Sandler M. Is the lung a ‘target organ’ in diabetes mellitus?. Arch Intern Med 1990; 150: 1385-1388
9 Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities. Diabetes Care 2008; 31 (Suppl. 02) S170-S180
10 Jagadapillai R, Rane MJ, Lin X. et al. Diabetic microvascular disease and pulmonary fibrosis: The contribution of platelets and systemic inflammation. Int J Mol Sci 2016; 17: pii: E1853
11 Groener JB, Oikonomou D, Cheko R. et al. Methylglyoxal and advanced glycation end products in patients with diabetes - What we know so far and the missing links. Exp Clin Endocrinol Diabetes 2017;
12 Zhang X, Liu Y, Shao R. et al. Cdc42-interacting protein 4 silencing relieves pulmonary fibrosis in STZ-induced diabetic mice via the Wnt/GSK-3beta/beta-catenin pathway. Exp Cell Res 2017; 359: 284-290
13 Oztay F, Sancar-Bas S, Gezginci-Oktayoglu S. etal. Exendin-4 partly ameliorates - hyperglycemia-mediated tissue damage in lungs of streptozotocin-induced diabetic mice. Peptides 2018; 99: 99-107
14 Kumar V, Fleming T, Terjung S. et al. Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair. Nucleic Acids Res 2017; 45: 10595-10613
15 Röhling M, Pesta D, Markgraf DF. et al. Metabolic determinants of impaired pulmonary function in patients with newly diagnosed type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes 2018; 126: 584-589
16 Spagnolo P, Kreuter M, Maher TM. et al. Metformin does not affect clinically relevant outcomes in patients with idiopathic pulmonary fibrosis. Respiration 2018; 1-9
17 Gaunaurd IA, Gomez-Marin OW, Ramos CF. et al. Physical activity and quality of life improvements of patients with idiopathic pulmonary fibrosis completing a pulmonary rehabilitation program. Respir Care 2014; 59: 1872-1879
18 Vainshelboim B. Exercise training in idiopathic pulmonary fibrosis: Is it of benefit?. Breathe (Sheff) 2016; 12: 130-138