Circulating Inflammatory Cytokine Responses to Endurance Exercise in Female Rowers

Jaak Jürimäe; Sille Vaiksaar; Priit Purge

doi:10.1055/a-0723-4421

International Journal of Sports Medicine, Inhaltsverzeichnis

Int J Sports Med 2018; 39(14): 1041-1048
DOI: 10.1055/a-0723-4421

Physiology & Biochemistry

Circulating Inflammatory Cytokine Responses to Endurance Exercise in Female Rowers

Jaak Jürimäe

¹Institute of Sport Sciences and Physiotherapy, University of Tartu,Tartu, Estonia

,

Sille Vaiksaar

¹Institute of Sport Sciences and Physiotherapy, University of Tartu,Tartu, Estonia

,

Priit Purge

¹Institute of Sport Sciences and Physiotherapy, University of Tartu,Tartu, Estonia

› Institutsangaben

Abstract

This investigation examined the effects of acute rowing exercise on a panel of 12 different inflammatory cytokines. Fifteen female rowers (18.3±1.6 yrs; 172.0±5.0 cm; 67.5±8.8 kg; maximal oxygen consumption [VO₂max]: 47.2±7.9 ml.min.⁻¹kg⁻¹) completed a 1-h endurance exercise (distance: 12.1±1.1 km; energy expenditure [EE]: 639±69 kcal; heart rate: 151±7 beats.min⁻¹; intensity: 79.6±3.5% of the second ventilatory turn point). Venous blood samples were analysed for interleukin (IL)-2, IL-4, IL-6, IL-8, IL-10, vascular endothelial growth factor (VEGF), interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), IL-1α, IL-1β, monocyte chemoattractant protein-1 (MCP-1) and epidermal growth factor (EGF) concentrations. Rowing exercise resulted increment (P<0.05) in IL-6, IL-8, VEGF and MCP-1. Exercise metabolic demand variables such as rating of perceived exertion (r=0.61), distance covered (r=0.60) and EE (r=0.57) were related (P<0.05) to changes in VEGF concentration. Cardiorespiratory fitness as measured by VO₂max was correlated with changes in IL-6 (r=–0.55; P<0.05) level. In conclusion, acute exercise-induced inflammatory reaction was induced by a significant increase in IL-6, IL-8, VEGF and MCP-1 concentrations. Variance in exercise-induced increases in inflammatory cytokines in response to prolonged endurance exercise was characterised by exercise metabolic demand and cardiorespiratory fitness measures in female rowers.

Key words

Inflammatory profile - female rowers - endurance exercise - vascular endothelial growth factor - interleukin-6

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