Adjuvante Therapie bei posttraumatischer Belastungsstörung

Bei der Behandlung posttraumatischer Belastungsstörungen (PTBS) stellen traumafokussierte Psychotherapieverfahren die Methode der ersten Wahl dar. Obwohl diese Verfahren nachweislich zu einer starken Symptomreduktion führen, bildet sich die PTBS-Symptomatik nicht bei allen Betroffenen vollständig zurück. Erste Befunde zum Einsatz von adjuvanten Therapieverfahren in der PTBS-Behandlung verweisen auf vielversprechendes Potenzial zur Steigerung der Wirksamkeit etablierter Verfahren.

• Literatur

• 1 Michael T, Sopp R, Maercker A. Posttraumatische Belastungsstörungen. Lehrbuch der Verhaltenstherapie, Band 2. Heidelberg: Springer; 2018: 105-124
• 2 Kirsch A, Equit M, Michael T. Adjuvante Verfahren. In: Schellong J, Epple F, Weidner K. Hrsg. Praxisbuch Psychotraumatologie. Stuttgart: Thieme; 2018: 137-140
• 3 Flatten G, Gast U, Hofmann A. et al. Posttraumatische Belastungsstörung: S3-Leitlinie und Quellentexte. Stuttgart: Schattauer; 2013: 147
• 4 National Institute for Health and Care Excellence. Post-traumatic stress disorder: management. 2005 Im Internet: https://www.nice.org.uk/guidance/cg26/resources/posttraumatic-stress-disorder-management-pdf-975329451205 Stand: 07.03.2019
• 5 Powers MB, Medina JL, Burns S. et al. Exercise Augmentation of Exposure Therapy for PTSD: Rationale and Pilot Efficacy Data. Cogn Behav Ther 2015; 44: 314-327
• 6 Rosaura Polak A, Witteveen AB, Denys D. et al. Breathing biofeedback as an adjunct to exposure in cognitive behavioral therapy hastens the reduction of PTSD symptoms: a pilot study. Appl Psychophys Biof 2015; 40: 25-31 Im Internet: http://cochranelibrary-wiley.com/o/cochrane/clcentral/articles/892/CN-01256892/frame.html Stand: 07.03.2019
• 7 Bentz D, Michael T, Dominique J-F. et al. Enhancing exposure therapy for anxiety disorders with glucocorticoids: from basic mechanisms of emotional learning to clinical applications. J Anx Dis 2010; 24: 223-230
• 8 Hill E, Zack E, Battaglini C. et al. Exercise and circulating cortisol levels: the intensity threshold effect. J Endocrinol Inv 2008; 31: 587-591
• 9 Schuch FB, Vancampfort D, Richards J. et al. Exercise as a treatment for depression: a meta-analysis adjusting for publication bias. J Psy Res 2016; 77: 42-51
• 10 de Kleine RA, Hendriks G-J, Kusters WJ. et al. A randomized placebo-controlled trial of D-cycloserine to enhance exposure therapy for posttraumatic stress disorder. Biol Psy 2012; 71: 962-968
• 11 Tuerk PW, Wangelin BC, Powers MB. et al. Augmenting treatment efficiency in exposure therapy for PTSD: a randomized double-blind placebo-controlled trial of yohimbine HCl. Cogn Beh Ther 2018; 1-21
• 12 Zoellner LA, Telch M, Foa EB. et al. Enhancing Extinction Learning in Posttraumatic Stress Disorder With Brief Daily Imaginal Exposure and Methylene Blue: a Randomized Controlled Trial. J Clin Psy 2017; 78: e782-e789 Im Internet: http://cochranelibrary-wiley.com/o/cochrane/clcentral/articles/338/CN-01405338/frame.html Stand: 07.03.2019
• 13 Yehuda R, Bierer LM, Pratchett LC. et al. Cortisol augmentation of a psychological treatment for warfighters with posttraumatic stress disorder: randomized trial showing improved treatment retention and outcome. Psychoneuroendocrin 2015; 51: 589-597 Im Internet: http://cochranelibrary-wiley.com/o/cochrane/clcentral/articles/125/CN-01040125/frame.html Stand: 07.03.2019
• 14 Flanagan JC, Sippel LM, Wahlquist A. et al. Augmenting Prolonged Exposure therapy for PTSD with intranasal oxytocin: A randomized, placebo-controlled pilot trial. J Psy Res 2018; 98: 64-69
• 15 Bürkner PC, Bittner N, Holling H. et al. D-cycloserine augmentation of behavior therapy for anxiety and obsessive-compulsive disorders: A meta-analysis. Plos One 2017; 12: 0173660
• 16 Ehlers A, Clark DM. A cognitive model of posttraumatic stress disorder. Behav Res Ther 2000; 38: 319-345
• 17 Ehlers A, Hackmann A, Michael T. Intrusive re-experiencing in post-traumatic stress disorder: Phenomenology, theory, and therapy. Memory 2004; 12: 403-415
• 18 Pfaltz MC, Michael T, Meyer AH. et al. Reexperiencing symptoms, dissociation, and avoidance behaviors in daily life of patients with PTSD and patients with panic disorder with agoraphobia. J Traum Stress 2013; 26: 443-450
• 19 Hilton L, Maher AR, Colaiaco B. et al. Meditation for posttraumatic stress: systematic review and meta-analysis. Psychol Trauma Theory Res Pract Pol 2017; 9: 453-460
• 20 Kearney DJ, McDermott K, Malte C. et al. Effects of participation in a mindfulness program for veterans with posttraumatic stress disorder: a randomized controlled pilot study. J Clin Psy 2013; 69: 14-27