Zusammenfassung
Inhalationsallergien bei Kindern erfordern eine umfassende Diagnostik und konsequente
Therapie. Das Behandlungsspektrum umfasst neben der Allergenkarenz die symptomatische
Pharmakotherapie und die kausale Allergie-Immuntherapie (AIT). Kinder sind eine wichtige
Zielgruppe für eine AIT, da sie aufgrund ihrer Langzeiteffekte und sekundär-präventiven
Eigenschaften den Verlauf der Erkrankung nachhaltig beeinflussen kann.
Abstract
Adequate diagnostical workup for respiratory allergies and consequent therapy in children
determine the individual course of disease. Therapy consists first of symptomatic
treatment and includes in the next step the important option of allergy immunotherapy
(AIT) as a causative treatment of disease. Children are an important target group
for AIT, since AIT offers a proven longterm effect including secondary preventive
properties with not only transiently reduced symptoms but moreover longstanding and
beneficial disease modification.
New strategies with AIT as primary and secondary preventive interventions are being
evaluated with the aim to reduce clinical appearance and the amount and extent of
sensitizations to allergens in high-risk children. Until implementation of such potentially
preventive strategies the currently more attractive early intervention is the early
adoption of AIT within the first 12 to 24 months of onset of symptoms as a first-line
treatment of allergic rhinitis.
Simplified treatment protocols can improve the willingness to perform an AIT and the
adherence and compliance of children and their parents. The overall goal is to make
AIT as the most important treatment modality available to more affected children.
Schlüsselwörter
Allergie-Immuntherapie - allergenspezifische Immuntherapie - Hyposensibilisierung
- Kinder - allergische Rhinitis - Asthma
Key words
Allergy immunotherapy - allergen specific immunotherapy - hyposensitization - children
- allergic rhinitis - asthma
