Allgemein- und Viszeralchirurgie up2date, Table of Contents Allgemein- und Viszeralchirurgie up2date 2020; 14(05): 487-502DOI: 10.1055/a-1092-7169 Leber, Galle, Pankreas, Milz Komplikationsmanagement nach Pankreaseingriffen Elke Demir , I. Ekin Demir , Helmut Friess Recommend Article Abstract Buy Article All articles of this category Operationen am Pankreas sind hochkomplexe viszeralchirurgische Eingriffe und haben entsprechende Komplikationsraten. Die Morbidität und Mortalität wird zusätzlich durch die Aggressivität des Pankreassekrets bei Pankreasfisteln und dessen schwerwiegende peripankreatische und systemische Auswirkungen bedingt. Die Diagnostik und Therapie ist komplex und erfordert herausragende klinische Expertise und interdisziplinäre Zusammenarbeit. Schlüsselwörter SchlüsselwörterPankreaschirurgie - postoperative Komplikation - Pankreasfistel - Galleleckage - Pankreasinsuffizienz Full Text References Literatur 1 Nimptsch U, Krautz C, Weber GF. et al. Nationwide in-hospital mortality following pancreatic surgery in Germany is higher than anticipated. Ann Surg 2016; 264: 1082-1090 doi:10.1097/SLA0000000000001693 2 Wu W, He X, Yang L. et al. Rising trends in pancreatic cancer incidence and mortality in 2000–2014. Clin Epidemiol 2018; 10: 789-797 doi:10.2147/CLEP.S160018 3 Robert Koch-Institut. Zentrum für Krebsregisterdaten. Berlin: 2020. . Im Internet (Stand: 06.09.2020): https://www.krebsdaten.de/Krebs/DE/Content/Krebsarten/Bauchspeicheldruesenkrebs/bauchspeicheldruesenkrebs_node.html 4 Mischinger H-J, Werkgartner G, Kornprat P. et al. Komplikationen in der Pankreaschirurgie. Wiener Klin Mag 2018; 21: 98-107 doi:10.1007/s00740-018-0226-1 5 Mackay TM, Wellner UF, van Rijssen LB. et al. Variation in pancreatoduodenectomy as delivered in two national audits. Br J Surg 2019; 106: 747-755 doi:10.1002/bjs.11085 6 Hackert T, Klaiber U, Hinz U. et al. Sphincter of Oddi botulinum toxin injection to prevent pancreatic fistula after distal pancreatectomy. Surgery 2017; 161: 1444-1450 doi:10.1016/j.surg.2016.09.005 7 Besselink MG, van Rijssen LB, Bassi C. et al. Definition and classification of chyle leak after pancreatic operation: A consensus statement by the International Study Group on Pancreatic Surgery. Surgery 2017; 161: 365-372 doi:10.1016/j.surg.2016.06.058 8 Bassi C, Marchegiani G, Dervenis C. et al. The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After. Surgery 2017; 161: 584-591 doi:10.1016/j.surg.2016.11.014 9 Horvath P, Beckert S, Nadalin S. et al. Pancreas-preserving surgical management of grade-C pancreatic fistulas after pancreatic head resection by external wirsungostomy. Langenbecks Arch Surg 2016; 401: 457-462 doi:10.1007/s00423-016-1423-2 10 Demir E, Abdelhai K, Demir IE. et al. Association of bacteria in pancreatic fistula fluid with complications after pancreatic surgery. BJS Open 2020; 4: 432-437 doi:10.1002/bjs5.50272 11 Bressan AK, Wahba M, Dixon E. et al. Completion pancreatectomy in the acute management of pancreatic fistula after pancreaticoduodenectomy: a systematic review and qualitative synthesis of the literature. HPB (Oxford) 2018; 20: 20-27 doi:10.1016/j.hpb.2017.08.036 12 Cheng Y, Briarava M, Lai M. et al. Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy. Cochrane Database Syst Rev 2017; (09) CD012257 13 Ecker BL, McMillan MT, Asbun HJ. et al. Characterization and optimal management of high-risk pancreatic anastomoses during pancreatoduodenectomy. Ann Surg 2018; 267: 608-616 doi:10.1097/SLA0000000000002327 14 Wente MN, Veit JA, Bassi C. et al. Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition. Surgery 2007; 142: 20-25 doi:10.1016/j.surg.2007.02.001 15 McMillan MT, Vollmer CM, Asbun HJ. et al. The Characterization and prediction of ISGPF grade C fistulas following pancreatoduodenectomy. J Gastrointest Surg 2016; 20: 262-276 doi:10.1007/s11605-015-2884-2 16 Floortje van Oosten A, Smits FJ, van den Heuvel DAF. et al. Diagnosis and management of postpancreatectomy hemorrhage: a systematic review and meta-analysis. HPB (Oxford) 2019; 21: 953-961 doi:10.1016/j.hpb.2019.02.011 17 Lu JW, Ding HF, Wu XN. et al. Intra-abdominal hemorrhage following 739 consecutive pancreaticoduodenectomy: Risk factors and treatments. J Gastroenterol Hepatol 2019; 34: 1100-1107 doi:10.1111/jgh.14560 18 Panwar R, Pal S. The International Study Group of Pancreatic Surgery definition of delayed gastric emptying and the effects of various surgical modifications on the occurrence of delayed gastric emptying after pancreatoduodenectomy. Hepatobiliary Pancreat Dis Int 2017; 16: 353-363 doi:10.1016/S1499-3872(17)60037-7 19 Ellis RJ, Gupta AR, Hewitt DB. et al. Risk factors for post-pancreaticoduodenectomy delayed gastric emptying in the absence of pancreatic fistula or intra-abdominal infection. J Surg Oncol 2019; 119: 925-931 doi:10.1002/jso.25398 20 Lu KH, Cao J, Oleson S. et al. Vagus nerve stimulation promotes gastric emptying by increasing pyloric opening measured with magnetic resonance imaging. Neurogastroenterol Motil 2018; 30: e13380 doi:10.1111/nmo.13380 21 Wente MN, Bassi C, Dervenis C. et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery 2007; 142: 761-768 doi:10.1016/j.surg.2007.05.005 22 Maus MK, Leers J, Herbold T. et al. Gastric outlet obstruction after esophagectomy: retrospective analysis of the effectiveness and safety of postoperative endoscopic pyloric dilatation. World J Surg 2016; 40: 2405-2411 doi:10.1007/s00268-016-3575-1 23 El Nakeeb A, El Sorogy M, Hamed H. et al. Biliary leakage following pancreaticoduodenectomy: Prevalence, risk factors and management. Hepatobil Pancreat Dis Int 2019; 18: 67-72 doi:10.1016/j.hbpd.2018.10.005 24 Duconseil P, Turrini O, Ewald J. et al. Biliary complications after pancreaticoduodenectomy: skinny bile ducts are surgeonsʼ enemies. World J Surg 2014; 38: 2946-2951 doi:10.1007/s00268-014-2698-5 25 Koch M, Garden OJ, Padbury R. et al. Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery. Surgery 2011; 149: 680-688 doi:10.1016/j.surg.2010.12.002 26 Sun YM, Wang Y, Mao YX. et al. The Safety and feasibility of enhanced recovery after surgery in patients undergoing pancreaticoduodenectomy: an updated meta-analysis. Biomed Res Int 2020; 2020: 7401276 doi:10.1155/2020/7401276 27 Birgin E, Reeg A, Teoule P. et al. Early postoperative pancreatitis following pancreaticoduodenectomy: what is clinically relevant postoperative pancreatitis?. HPB (Oxford) 2019; 21: 972-980 doi:10.1016/j.hpb.2018.11.006 28 Connor S. Defining post-operative pancreatitis as a new pancreatic specific complication following pancreatic resection. HPB (Oxford) 2016; 18: 642-651 doi:10.1016/j.hpb.2016.05.006 29 Chen H, Wang W, Ying X. et al. Predictive factors for postoperative pancreatitis after pancreaticoduodenectomy: A single-center retrospective analysis of 1465 patients. Pancreatology 2020; 20: 211-216 doi:10.1016/j.pan.2019.11.014 30 Wu L, Nahm CB, Jamieson NB. et al. Risk factors for development of diabetes mellitus (Type 3c) after partial pancreatectomy: A systematic review. Clin Endocrinol (Oxford) 2020; 92: 396-406 doi:10.1111/cen.14168 31 Schorn S, Demir IE, Vogel T. et al. Mortality and postoperative complications after different types of surgical reconstruction following pancreaticoduodenectomy-a systematic review with meta-analysis. Langenbecks Arch Surg 2019; 404: 141-157 doi:10.1007/s00423-019-01762-5 32 Schemmer P, Schultze DP, Contin P. et al. Antireflux jejunoplasty for recurrent cholangitis. J Am Coll Surg 2011; 212: e28-e32 doi:10.1016/j.jamcollsurg.2011.01.058
