Therapeutisches Drug Monitoring (TDM) in der antiinfektiven Therapie – von der Theorie zur Praxis

Die Medusa-Studie zeigte, dass in Deutschland nur etwa 58 % der Patienten mit schwerer Sepsis und septischem Schock eine adäquate Antibiotikatherapie erhielten [1], die einen klaren Überlebensvorteil von 11 % bot. Neben eines septischen Schocks und multiresistenter Erreger (MRE) ist eine inadäquate Antibiotikatherapie bei septischen Patienten eine unabhängige Variable der Gesamtmortalität [2].

• Literatur

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