Onkologie up2date, Table of Contents Onkologie up2date 2020; 2(03): 207-220DOI: 10.1055/a-1176-5097 Tumoren des Gastrointestinaltraktes Die unklare Leberraumforderung Christoph Roderburg‡ , Sven H. Loosen‡ , Philipp Bruners , Tom Luedde Recommend Article Abstract Buy Article All articles of this category Unklare Leberläsionen stellen ein sehr häufiges klinisches Problem dar, etwa im Kontext von sonografischen Routineuntersuchungen in der hausärztlichen oder internistischen Praxis. Die zentrale Aufgabe in der Diagnostik besteht darin, die Gutartigkeit der Läsionen zu belegen und eine maligne Ursache möglichst sicher auszuschließen, wobei eine genaue Zuordnung jedoch nicht immer zu erreichen ist. Full Text References Literatur 1 Dietrich C. Contrast-Enhanced Ultrasound of Benign Focal Liver Lesions. Ultraschall der Medizin. Eur J Ultrasound 2019; 40: 12-29 2 Torzilli G, Minagawa M, Takayama T. et al. Accurate preoperative evaluation of liver mass lesions without fine-needle biopsy. Hepatology 1999; 30: 889-893 3 Rungsinaporn K, Phaisakamas T. Frequency of abnormalities detected by upper abdominal ultrasound. J Med Assoc Thai 2008; 91: 1072-1075 4 Glinkova V, Shevah O, Boaz M. et al. Hepatic haemangiomas: possible association with female sex hormones. Gut 2004; 53: 1352-1355 5 Liu X, Yang Z, Tan H. et al. Giant liver hemangioma with adult Kasabach-Merritt syndrome: Case report and literature review. Medicine (Baltimore) 2017; 96: e7688 6 Grazioli L, Ambrosini R, Frittoli B. et al. Primary benign liver lesions. Eur J Radiol 2017; 95: 378-398 7 Dietrich CF, Tana C, Caraiani C. et al. Contrast enhanced ultrasound (CEUS) imaging of solid benign focal liver lesions. Expert Rev Gastroenterol Hepatol 2018; 12: 479-489 8 Navarro AP, Gomez D, Lamb CM. et al. Focal nodular hyperplasia: a review of current indications for and outcomes of hepatic resection. HPB 2014; 16: 503-511 9 Edmondson HA, Henderson B, Benton B. Liver-cell adenomas associated with use of oral contraceptives. N Engl J Med 1976; 294: 470-472 10 Torbenson M. Hepatic Adenomas: Classification, Controversies, and Consensus. Surg Pathol Clin 2018; 11: 351-366 11 European Association for the Study of the Liver (EASL). EASL Clinical Practice Guidelines on the management of benign liver tumours. J Hepatol 2016; 65: 386-398 12 Nault JC, Paradis V, Cherqui D. et al. Molecular classification of hepatocellular adenoma in clinical practice. J Hepatol 2017; 67: 1074-1083 13 Laumonier H, Bioulac-Sage P, Laurent C. et al. Hepatocellular adenomas: magnetic resonance imaging features as a function of molecular pathological classification. Hepatology 2008; 48: 808-818 14 Galle PR, Forner A, Llovet JM. et al. EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. J Hepatol 2018; 69: 182-236 15 Dietrich CF, Jenssen C. Der zufällig entdeckte Leberrundherd. Dtsch Med Wochenschr 2012; 137: 2099-2116 16 van der Pol CB, Lim CS, Sirlin CB. et al. Accuracy of the liver imaging reporting and data system in computed tomography and magnetic resonance image analysis of hepatocellular carcinoma or overall malignancy – a systematic review. Gastroenterology 2019; 156: 976-986 17 Razumilava N, Gores GJ. Cholangiocarcinoma. Lancet 2014; 383: 2168-2179 18 Van Beers BE. Diagnosis of cholangiocarcinoma. HPB (Oxford) 2008; 10: 87-93 19 de Ridder J, de Wilt JHW, Simmer F. et al. Incidence and origin of histologically confirmed liver metastases: an explorative case-study of 23154 patients. Oncotarget 2016; 7: 55368-55376 20 Cantisani V, Grazhdani H, Fioravanti C. et al. Liver metastases: Contrast-enhanced ultrasound compared with computed tomography and magnetic resonance. World J Gastroenterol 2014; 20: 9998-10007