Abklärung erhöhter Blutungsneigung – Schritt für Schritt

Das Leitsymptom der hämorrhagischen Diathese ist die Blutungsneigung, deren Ausprägung maßgeblich von der zugrunde liegenden Hämostasestörung beeinflusst wird. Unterteilt werden kann in thrombozytäre, plasmatische und vaskuläre Ursachen. Zentraler Bestandteil der Diagnostik ist neben der individuellen Blutungs- und Familienanamnese die differenzierte Labordiagnostik.

Abstract

The main symptom of hemorrhagic diathesis is an increased bleeding tendency. Due to the subjectivity of various features of the bleeding history, unclarity of the family history, and an individualization of the extent of diagnostic the evaluation of a suspected bleeding disorder represents a challenging endeavour in hematology. Hemorrhagic diathesis can be divided into the following sub-categories: disorders in primary hemostasis (e. g. von Willebrand disease, different causes of thrombocytopenia), secondary hemostasis (e. g. hemophilia A and B, Vitamin K deficiency) and fibrinolysis, and in connective tissue or vascular formation. This article reviews available diagnostic methods for bleeding disorders, from structured patient history to highly specialized laboratory diagnosis.

Schlüsselwörter

Blutungsstörung - Hämostase - Blutgerinnungsstörungen - Diagnose

Key words

bleeding disorder - hemostasis - blood coagulation disorders - diagnosis

Publication History

Article published online:
13 October 2021

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