Synthesis, Table of Contents Synthesis 2021; 53(13): 2240-2252DOI: 10.1055/a-1384-1967 paper Diastereoselective trans Cyclopropanation of 3-Alkylidene Oxindoles with In Situ Generated α-Diazo Carbonyls or α,β-Unsaturated Diazo Compounds Sayan Pramanik a Department of Chemistry, University of Calcutta, 92 APC Road, Kolkata 700009, India , Suman Ray b Department of Chemistry, Presidency University, Kolkata 700073, India , Suvendu Maity c Department of Chemistry, R. K. Mission Residential College, Narendrapur, Kolkata 700103, India , Prasanta Ghosh c Department of Chemistry, R. K. Mission Residential College, Narendrapur, Kolkata 700103, India , Chhanda Mukhopadhyay ∗ a Department of Chemistry, University of Calcutta, 92 APC Road, Kolkata 700009, India › Author Affiliations Recommend Article Abstract Buy Article All articles of this category Abstract An efficient diastereoselective trans cyclopropanation of 3-alkylidene oxindoles with in situ generated α-diazo carbonyl compounds or α,β-unsaturated diazo compounds under metal-free conditions has been developed to synthesize 3-spirocyclopropyl-2-oxindole derivatives. The procedure is based on the 1,3-dipolar character of the corresponding diazo compounds under base-catalyzed conditions. The method has a wide substrate scope and uses easily available starting materials. Key words Key wordsdiastereoselectivity - trans cyclopropanation - diazo compounds - 1,3-dipoles - spiro compounds - oxindoles Full Text References References 1a Nicolaou KC, Vourloumis D, Winssinger N, Baran PS. Angew. Chem. Int. 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