Vaskuläre Malformationen im Hals-Nasen-Ohren-Bereich

Vaskuläre Malformationen sind seltene angeborene Gefäßerkrankungen des venösen, lymphatischen und arteriellen Gefäßsystems, die jedes Organsystem betreffen können, jedoch besonders häufig im Kopf-Hals-Bereich auftreten. Ziel des Beitrags ist es, die verschiedenen Typen der vaskulären Malformationen des Kopf-Hals-Bereichs sowie ihre Symptome, Diagnostik und Therapie vorzustellen.

Publication History

Article published online:
06 July 2021

• Literatur

• 1 International Society for the Study of Vascular Anomalies (ISSVA). ISSVA classification for vascular anomalies. 2018 Verfügbar unter (Stand 21.10.2020): https://www.issva.org/UserFiles/file/ISSVA-Classification-2018.pdf
• 2 Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg 1982; 69: 412-422
• 3 Rodriguez-Laguna L, Ibañez K, Gordo G. et al. CLAPO syndrome: identification of somatic activating PIK3CA mutations and delineation of the natural history and phenotype. Genet Med 2018; 20 : 882-889 DOI: 10.1038/gim.2017.200.
• 4 Sadick M, Wohlgemuth WA, Huelse R. et al. Interdisciplinary management of head and neck vascular anomalies: clinical presentation, diagnostic findings and minimalinvasive therapies. Eur J Radiol Open 2017; 4: 63-68 DOI: 10.1016/j.ejro.2017.05.001.
• 5 Park H, Kim JS, Park H. et al. Venous malformations of the head and neck: a retrospective review of 82 cases. Arch Plast Surg 2019; 46 (01) 2333 DOI: 10.5999/aps.2018.00458.
• 6 Hung JW, Leung MW, Liu CS. et al. Venous, malformation and localized intravascular coagulopathy in children. Eur J Pediatr Surg 2017; 27: 181-184 DOI: 10.1055/s-0036-1582241.
• 7 Eivazi B, Werner JA. Extrakranielle vaskuläre Fehlbildungen (Hämangiome und vaskuläre Malformationen) im Kindes- und Jugendalter – Diagnostik, Klinik und Therapie. Laryngorhinootologie 2014; 93 (Suppl. 01) S185-S202 DOI: 10.1055/s-0033-1363216.
• 8 Faurschou A, Olesen AB, Leonardi-Bee J. et al. Lasers or light sources for treating port-wine stains. Cochrane Database Syst Rev 2011; 11: CD007152
• 9 Wiegand S, Eivazi B, Barth PJ. et al. Pathogenesis of lymphangiomas. Virchows Arch 2008; 453: 1-8 DOI: 10.1007/s00428-008-0611-z.
• 10 Wassef M, Blei F, Adams D. et al. ISSVA Board and Scientific Committee. Vascular anomalies classification: recommendations from the International Society for the Study of Vascular Anomalies. Pediatrics 2015; 136: e203-e214
• 11 Wiegand S, Eivazi B, Zimmermann AP. et al. Microcystic lymphatic malformations of the tongue: diagnosis, classification, and treatment. Arch Otolaryngol Head Neck Surg 2009; 135: 976-983
• 12 Adams MT, Saltzman B, Perkins JA. Head and neck lymphatic malformation treatment: a systematic review. Otolaryngol Head Neck Surg 2012; 147: 627-639
• 13 Wiegand S, Eivazi B, Zimmermann AP. et al. Sclerotherapy of lymphangiomas of the head and neck. Head Neck 2011; 33: 1649-1655
• 14 Wiegand S, Wichmann G, Dietz A. Treatment of lymphatic malformation with the mTOR inhibitor sirolimus. A systematic review. Lymph Res Biol 2018; 16: 330-339
• 15 Qiao C, Richter GT, Pan W. et al. Extracranial arteriovenous malformations: from bedside to bench. Mutagenesis 2019; 34: 299-306
• 16 Kohout MP, Hansen M, Pribaz JJ. et al. Arteriovenous malformations of the head and neck: natural history and management. Plast Reconstr Surg 1998; 102: 643-654
• 17 Richter GT, Suen JY. Clinical course of arteriovenous malformations of the head and neck: a case series. Otolaryngol Head Neck Surg 2010; 142: 184-190 DOI: 10.1016/j.otohns.2009.10.023.
• 18 Nair SC. Vascular anomalies of the head and neck region. J Maxillofac Oral Surg 2018; 17: 1-12
• 19 Li C, Yu J, Li K. et al. Dural arteriovenous fistula of the lateral foramen magnum region: a review. Interv Neuroradiol 2018; 24: 425-434 DOI: 10.1177/1591019918770768.