Stiff-Person-Syndrom – Ein Update zu Symptomen, Diagnostik und Therapie

Das Stiff-Person-Syndrom ist eine seltene Autoimmunerkrankung. Gemeinsam ist allen Stiff-Person-Spektrums-Erkrankungen (SPSE) das klinische Bild einer fluktuierenden, meist rumpfbetonten und stark stimulussensitiven Steifigkeit mit Spasmen. Dieser Beitrag fasst die klinische Symptomatik sowie die diagnostischen Untersuchungsmethoden und Therapieoptionen zusammen.

Schlüsselwörter

Stiff-Person-Syndrom - Stiff-Person-Spektrums-Erkrankungen - Glutamatdecarboxylase-Antikörper - neuronale Antikörper - GABA - Glycin-Rezeptor-Antikörper - Amphiphysin-Antikörper

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