Download PDF
neuroreha 2021; 13(03): 117-124
DOI: 10.1055/a-1531-8201
Schwerpunkt

Neurophysiologische Grundlagen des normalen und gestörten Schluckaktes

Malte Roderigo
,
Tobias Warnecke
,
Rainer Dziewas
,
Sonja Suntrup-Krüger
› Further Information
Also available at
    Permissions and Reprints

Beim Schlucken handelt es sich um einen überlebenswichtigen Vorgang, der die Aufnahme von Nahrung, Flüssigkeiten und Speichel ermöglicht und der Reinigung und dem Schutz von Mundhöhle, Zunge und Zähnen dient. Darüber hinaus werden die Atmungsorgane (Trachea, Lunge) durch einen intakten Schluckakt vor eindringendem Fremdmaterial und damit einhergehend auch Krankheitserregern geschützt. Man spricht umgangssprachlich nicht ohne Grund von „Verschlucken“, wenn es infolge eines Kontakts von Nahrung oder Flüssigkeiten mit den sensiblen Strukturen der Atemwege zur Auslösung des Hustenreflexes kommt.



Publication History

Article published online:
13 September 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Warnecke T, Dziewas R. Neurogene Dysphagien. Diagnostik und Therapie. 2nd ed.. Stuttgart: Kohlhammer; 2018. https://ebookcentral.proquest.com/lib/gbv/detail.action?docID=5371885 Stand: 14.07.2021
    CrossrefSearch in Google Scholar
  • 2 Clavé P, Shaker R. Dysphagia. Current reality and scope of the problem. Nature Reviews: Gastroenterology & Hepatology 2015; 12: 259-270
    CrossrefPubMedSearch in Google Scholar
  • 3 Wirth R, Dziewas R, Beck AM. et al. Oropharyngeal dysphagia in older persons – from pathophysiology to adequate intervention: A review and summary of an international expert meeting. Clinical Interventions in Aging 2016; 11: 189-208
    CrossrefPubMedSearch in Google Scholar
  • 4 Turley R, Cohen S. Impact of voice and swallowing problems in the elderly. Otolaryngology – Head and Neck Surgery 2009; 140: 33-36
    CrossrefPubMedSearch in Google Scholar
  • 5 Logemann JA, Pauloski BR, Rademaker AW. et al. Temporal and biomechanical characteristics of oropharyngeal swallow in younger and older men. In: Journal of Speech, Language, and Hearing Research 2000; 43: 1264-1274
    CrossrefPubMedSearch in Google Scholar
  • 6 Teismann IK, Steinstraeter O, Schwindt W. et al. Age-related changes in cortical swallowing processing. Neurobiology of Aging 2010; 31: 1044-1050
    CrossrefPubMedSearch in Google Scholar
  • 7 Lin LC, Wu SC, Chen HS. et al. Prevalence of impaired swallowing in institutionalized older people in Taiwan. Journal of the American Geriatrics Society 2002; 50: 1118-1123
    CrossrefPubMedSearch in Google Scholar
  • 8 Butler SG, Stuart A, Merkley L. et al. Penetration and aspiration in healthy older adults as assessed during endoscopic evaluation of swallowing. The Annals of Otology, Rhinology, and Laryngology 2009; 118: 190-198
    CrossrefPubMedSearch in Google Scholar
  • 9 Leopold NA, Daniels SK. Supranuclear control of swallowing. Dysphagia 2010; 25: 250-257
    CrossrefPubMedSearch in Google Scholar
  • 10 Humbert IA, Fitzgerald M, McLaren DG. et al. Neurophysiology of swallowing: Effects of age and bolus type. NeuroImage 2009; 44: 982-991
    CrossrefPubMedSearch in Google Scholar
  • 11 Dziewas R, Sörös P, Ishii R. et al. Neuroimaging evidence for cortical involvement in the preparation and in the act of swallowing. NeuroImage 2003; 20: 135-144
    CrossrefPubMedSearch in Google Scholar
  • 12 Hamdy S, Aziz Q, Rothwell JC. et al. The cortical topography of human swallowing musculature in health and disease. Nature Medicine 1996; 2: 1217-1224
    CrossrefPubMedSearch in Google Scholar
  • 13 Teismann IK, Dziewas R, Steinstraeter O. et al. Time-dependent hemispheric shift of the cortical control of volitional swallowing. Human Brain Mapping 2009; 30: 92-100
    CrossrefPubMedSearch in Google Scholar
  • 14 Mihai PG, Otto M, Platz T. et al. Sequential evolution of cortical activity and effective connectivity of swallowing using fMRI. Human Brain Mapping 2014; 35: 5962-5973
    CrossrefPubMedSearch in Google Scholar
  • 15 Robbins J, Levine RL, Maser A. et al. Swallowing after unilateral stroke of the cerebral cortex. Archives of Physical Medicine and Rehabilitation 1993; 74: 1295-1300
    CrossrefPubMedSearch in Google Scholar
  • 16 Suntrup S, Kemmling A, Warnecke T. et al. The impact of lesion location on dysphagia incidence, pattern and complications in acute stroke. Part 1: Dysphagia incidence, severity and aspiration. European Journal of Neurology 2015; 22: 832-838
    CrossrefPubMedSearch in Google Scholar
  • 17 Teismann IK, Suntrup S, Warnecke T. et al. Cortical swallowing processing in early subacute stroke. BMC Neurology 2011; 11: 34
    CrossrefPubMedSearch in Google Scholar
  • 18 Hamdy S, Aziz Q, Rothwell JC. et al. Recovery of swallowing after dysphagic stroke relates to functional reorganization in the intact motor cortex. Gastroenterology 1998; 115: 1104-1112
    CrossrefPubMedSearch in Google Scholar
  • 19 Dziewas R, Teismann IK, Suntrup S. et al. Cortical compensation associated with dysphagia caused by selective degeneration of bulbar motor neurons. Human Brain Mapping 2009; 30: 1352-1360
    CrossrefPubMedSearch in Google Scholar
  • 20 Teismann IK, Warnecke R, Suntrup S. et al. Cortical processing of swallowing in ALS patients with progressive dysphagia: A magnetoencephalographic study. PloSone 2011; 6: e19987
    CrossrefPubMedSearch in Google Scholar
  • 21 Suntrup S, Teismann I, Bejer J. et al. Evidence for adaptive cortical changes in swallowing in Parkinson’s disease. Brain 2013; 136: 726-738
    CrossrefPubMedSearch in Google Scholar
  • 22 Pisegna JM, Kaneoka A, Pearson W. et al. Effects of non-invasive brain stimulation on post-stroke dysphagia: A systematic review and meta-analysis of randomized controlled trials. Clinical Neurophysiology 2016; 127: 956-968
    CrossrefPubMedSearch in Google Scholar
  • 23 Suntrup-Krueger S, Ringmaier C, Muhle P. et al. Randomized trial of transcranial direct current stimulation for poststroke dysphagia. Annals of neurology 2018; 83: 328-340
    CrossrefPubMedSearch in Google Scholar
  • 24 Bath PM, Woodhouse LJ, Suntrup-Krueger S. et al. Pharyngeal electrical stimulation for neurogenic dysphagia following stroke, traumatic brain injury or other causes: Main results from the PHADER cohort study. EClinicalMedicine 2020; 28: 100608
    CrossrefPubMedSearch in Google Scholar
  • 25 Dziewas R, Stellato R, van der I Tweel. et al. Pharyngeal electrical stimulation for early decannulation in tracheotomised patients with neurogenic dysphagia after stroke (PHAST-TRAC): A prospective, single-blinded, randomised trial. The Lancet Neurology 2018; 17: 849-859
    CrossrefPubMedSearch in Google Scholar