Gemeinsame Stellungnahme der DGHO und DGVS zur Nutzenbewertung von Nivolumab (metastasiertes kolorektales Karzinom, dMMR oder MSI-H, vorbehandelte Patient*innen, Kombination mit Ipilimumab)

Inhaltsverzeichnis	Seite
1. Zusammenfassung	111
2. Einleitung	112
3. Stand des Wissens	112
4. Dossier und Bewertung von Nivolumab (Opdivo®)	113
4.1. Zweckmäßige Vergleichstherapie	113
4.2. Studien	113
4.3. Endpunkte	113
4.3.1. Mortalität	113
4.3.2. Morbidität	113
4.3.2.1. Progressionsfreie Überlebenszeit und Remissionsrate	113
4.3.2.2. Remissionsrate	113
4.3.2.3. Lebensqualität/Patient-Reported Outcome	113
4.3.2.4. Nebenwirkungen	114
4.4 Bericht des IQWiG	114
5. Klinische Bewertung des Nutzens	114
6. Ausmaß des Zusatznutzens	114
Literatur	114

Publication History

Article published online:
18 January 2022

• Literatur

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