Widersprüchliche Ergebnisse von Metaanalysen haben zu einer
Verunsicherung hinsichtlich der Sicherheit von Vitamin-E-Supplementationen
geführt. Ein genauer Blick auf die Studien zeigt, dass oft
unterschiedliche Einschlusskriterien und verschiedene Methoden für die
statistischen Analysen zugrunde lagen und daher die heterogene Datengrundlage
keine eindeutige Evidenzbewertung zulässt. Bei Einnahmemengen von
1000 mg/Tag gilt Vitamin E als sicher.
2
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– inconsistent results of different meta-analytic approaches. Cell Mol Biol (Noisy-le-grand) 2009; 55: OL1111-OL1120
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Bjelakovic G,
Nikolova D,
Gluud LL.
et al. Mortality in randomized trials of antioxidant supplements for primary and
secondary prevention: systematic review and meta-analysis. JAMA 2007; 297: 842-857
16
Bjelakovic G,
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patients with various diseases. Cochrane Database Syst Rev 2012; 3: CD007176
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Jiang S,
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et al. Meta-analysis: low-dose intake of vitamin E combined with other vitamins or
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