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Synthesis 2022; 54(12): 2749-2764
DOI: 10.1055/a-1755-3832
DOI: 10.1055/a-1755-3832
short review
Synthetic Approaches for the Construction of Five- and Six-Membered Silaazacycles
We are grateful to financial support from the National Natural Science Foundation of China (21921002, 22171191), the Open Research Fund of Chengdu University of Traditional Chinese Medicine Key Laboratory of Systematic Research of Distinctive Chinese Medicine Resources in Southwest China (2020LF2003), and the Science and Technology Department of Sichuan Province (2020YFS0186).
Abstract
Silaazacycles (or azasilacycles), containing both nitrogen and silicon atoms, are appealing ring structures in the development of silicon-containing functional molecules. The development of general and efficient methods towards these motifs has therefore attracted considerable attention from synthetic chemists. This short review intends to highlight representative advances in the synthesis of five- and six-membered silaazacycles.
1 Introduction
2 Five-Membered Silaazacycles
2.1 Five-Membered Silaazacycles bearing a 1,2-N/Si Moiety
2.2 Five-Membered Silaazacycles bearing a 1,3-N/Si Moiety
3 Six-Membered Silaazacycles
3.1 Six-Membered Silaazacycles bearing a 1,2-N/Si Moiety
3.2 Six-Membered Silaazacycles bearing a 1,3-N/Si Moiety
3.3 Six-Membered Silaazacycles bearing a 1,4-N/Si Moiety
4 Conclusion
Key words
silaazacycles - azasilacycles - cyclization - ring expansion - carbon-silicon switching - N-substitutionPublication History
Received: 26 December 2021
Accepted after revision: 31 January 2022
Accepted Manuscript online:
31 January 2022
Article published online:
09 March 2022
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