Subscribe to RSS
DOI: 10.1055/a-1768-1123
Robotisch gestützte Enukleation einer zystischen Neoplasie des Pankreaskopfes
Robotic-assisted Enucleation of a Cystic Neoplasm in the Head of the Pancreas
Zusammenfassung
Laut aktuellen revidierten Fukuoka-Leitlinien besteht die Indikation zur Resektion von BD-IPMN des Pankreas mit Worrisome Features, da hier ein Risiko der malignen Entartung von bis zu 30% besteht. Die Resektion kann bei fehlenden klinischen, bildmorphologischen und laborchemischen Malignitätszeichen als eine nicht anatomische, lokale Exzision durchgeführt werden.
Eine robotische Enukleation bei benignen Raumforderungen der Bauchspeicheldrüse stellt eine sehr gute Alternative zu den resezierenden Verfahren, insbesondere zu denjenigen in offener Technik, dar. Diese operative Behandlungsoption wird bei einem Mindestabstand bis zum pankreatischen Hauptgang von mindestens 2 mm im „International consensus statement on robotic pancreatic surgery“ nahegelegt.
Neben den bekannten Vorteilen der minimalinvasiven Chirurgie führt diese parenchymsparende Methode zum Erhalt von endo- und exokriner Funktion (ca. 90%) und zu einem progressfreien 10-Jahres-Überleben von ca. 75% bei etwas erhöhter Morbidität (ca. 60%) verglichen mit den resezierenden Verfahren.
Der folgende Videobeitrag präsentiert das Operationsvideo einer robotischen Zystenenukleation (bei Verdacht auf eine BD-IPMN mit Worrisome Features) im Pankreaskopf und Processus uncinatus bei einer 62-jährigen Patientin mit besonderer Betonung der wichtigsten vaskulären Landmarken, Besonderheiten der Herangehensweise und Vorteile der robotischen Technik.
Abstract
According to current revised Fukuoka guidelines, there is an indication for resection of BD-IPMN of the pancreas with “worrisome features”, as there is a risk of malignant degeneration of up to 30%. This can be performed as a non-anatomical local excision in the absence of clinical, radiological and laboratory signs of malignancy.
Robotic enucleation for benign tumours of the pancreas is a very good alternative to resecting procedures, especially those using open techniques. This surgical treatment option is recommended by the “International consensus statement on robotic pancreatic surgery” in a case of a minimum distance to the main pancreatic duct of at least 2 mm.
In addition to the known advantages of minimally invasive surgery, this parenchyma-sparing approach results in preservation of endo- and exocrine function (ca. 90%) and 10-year progression-free survival of ca. 75% with slightly increased morbidity (ca. 60%) compared with resecting procedures.
The following video article presents the surgical video of a robotic cyst enucleation (for suspected BD-IPMN with “worrisome features”) in the pancreatic head and uncinate process in a 62-year-old female patient with special emphasis on the most important vascular landmarks, special features of the approach and advantages of the robotic technique
Schlüsselwörter
Pankreaschirurgie - IPMN - Robotic - Enukleation - minimalinvasiv - parenchymsparendKeywords
pancreatic surgery - IPMN - robotics - enucleation - minimally invasive - parenchym sparingPublication History
Received: 31 January 2022
Accepted: 08 February 2022
Article published online:
04 April 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Tanaka M, Fernández-Del Castillo C, Kamisawa T. et al. Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas. Pancreatology 2017; 17: 738-753
- 2 Falconi M, Mantovani W, Crippa S. et al. Pancreatic insufficiency after different resections for benign tumours. Br J Surg 2008; 95: 85-91
- 3 Hüttner FJ, Koessler-Ebs J, Hackert T. et al. Meta-analysis of surgical outcome after enucleation versus standard resection for pancreatic neoplasms. Br J Surg 2015; 102: 1026-1036
- 4 Beger HG, Mayer B, Vasilescu C. et al. Long-term Metabolic Morbidity and Steatohepatosis Following Standard Pancreatic Resections and Parenchyma-sparing, Local Extirpations for Benign Tumor: A Systematic Review and Meta-analysis. Ann Surg 2021;
- 5 Sauvanet A, Gaujoux S, Blanc B. et al. Parenchyma-sparing pancreatectomy for presumed noninvasive intraductal papillary mucinous neoplasms of the pancreas. Ann Surg 2014; 260: 364-371
- 6 Beger HG, Siech M, Poch B. et al. Limited surgery for benign tumours of the pancreas: a systematic review. World J Surg 2015; 39: 1557-1566
- 7 Kaiser J, Fritz S, Klauss M. et al. Enucleation: A treatment alternative for branch duct intraductal papillary mucinous neoplasms. Surgery 2017; 161: 602-610
- 8 Strobel O, Cherrez A, Hinz U. et al. Risk of pancreatic fistula after enucleation of pancreatic tumours. Br J Surg 2015; 102: 1258-1266
- 9 Liu R, Wakabayashi G, Palanivelu C. et al. International consensus statement on robotic pancreatic surgery. Hepatobiliary Surg Nutr 2019; 8: 345-360
- 10 Asbun HJ, Moekotte AL, Vissers FL. et al. The Miami International Evidence-based Guidelines on Minimally Invasive Pancreas Resection. Ann Surg 2020; 271: 1-14
- 11 Müller-Debus CF, Thomaschewski M, Zimmermann M. et al. Robot-Assisted Pancreatic Surgery: A Structured Approach to Standardization of a Program and of the Operation. Visc Med 2020; 36: 104-112
- 12 Thomaschewski M, Zimmermann M, Honselmann K. et al. Robotisch assistierte Resektion eines zentralen neoadjuvant behandelten Pankreaskarzinoms mit En-bloc-Resektion des Truncus coeliacus (modifizierte Appleby-Operation). Zentralbl Chir 2021; 146: 552-559
- 13 European Study Group on Cystic Tumours of the Pancreas. European evidence-based guidelines on pancreatic cystic neoplasms. Gut 2018; 67: 789-804
- 14 Buerlein RCD, Shami VM. Management of pancreatic cysts and guidelines: what the gastroenterologist needs to know. Ther Adv Gastrointest Endosc 2021; 14
- 15 Vege SS, Ziring B, Jain R. et al. American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts. Gastroenterology 2015; 148: 819-822
- 16 Keane MG, Afghani E. A Review of the Diagnosis and Management of Premalignant Pancreatic Cystic Lesions. J Clin Med Res 2021; 10: 1284
- 17 Teoh AY, Seo DW, Brugge W. et al. Position statement on EUS-guided ablation of pancreatic cystic neoplasms from an international expert panel. Endosc Int Open 2019; 7: E1064-E1077
- 18 Cameron JL, Riall TS, Coleman J. et al. One thousand consecutive pancreaticoduodenectomies. Ann Surg 2006; 244: 10-15
- 19 Strobel O, Neoptolemos J, Jäger D. et al. Optimizing the outcomes of pancreatic cancer surgery. Nat Rev Clin Oncol 2019; 16: 11-26
- 20 Wellner UF, Keck T. Quality Indicators in Pancreatic Surgery: Lessons Learned from the German DGAV StuDoQ|Pancreas Registry. Visc Med 2017; 33: 126-130
- 21 Elta GH, Enestvedt BK, Sauer BG. et al. ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts. Am J Gastroenterol 2018; 113: 464-479
- 22 Blue Milk Srl. iCyst. Accessed October 13, 2021 at: https://apps.apple.com/de/app/icyst/id1479833485
- 23 Overbeek KA, Kamps A, van Riet PA. et al. Pancreatic cyst surveillance imposes low psychological burden. Pancreatology 2019; 19: 1061-1066
- 24 Sharib J, Esserman L, Koay EJ. et al. Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective. Surgery 2020; 168: 601-609
- 25 Djordjevic V, Grubor N, Kovac JD. et al. Comparison of Preoperative Evaluation with the Pathological Report in Intraductal Papillary Mucinous Neoplasms: A Single-Center Experience. J Clin Med Res 2021; 10: 678
- 26 Lekkerkerker SJ, Besselink MG, Busch OR. et al. Comparing 3 guidelines on the management of surgically removed pancreatic cysts with regard to pathological outcome. Gastrointest Endosc 2017; 85: 1025-1031
- 27 Lobo JM, Scheiman JM, Zaydfudim VM. et al. Clinical and Economic Outcomes of Patients Undergoing Guideline-Directed Management of Pancreatic Cysts. Am J Gastroenterol 2020; 115: 1689-1697
- 28 Jang JY, Park T, Lee S. et al. Proposed Nomogram Predicting the Individual Risk of Malignancy in the Patients With Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas. Ann Surg 2017; 266: 1062-1068
- 29 Jung W, Park T, Kim Y. et al. Validation of a nomogram to predict the risk of cancer in patients with intraductal papillary mucinous neoplasm and main duct dilatation of 10 mm or less. Br J Surg 2019; 106: 1829-1836
- 30 Lee SJ, Park SY, Hwang DW. et al. Surgical Decisions Based on a Balance between Malignancy Probability and Surgical Risk in Patients with Branch and Mixed-Type Intraductal Papillary Mucinous Neoplasm. J Clin Med Res 2020; 9
- 31 Kabir T, Tan ZZX, Syn N. et al. Minimally-invasive versus open enucleation for pancreatic tumours: A propensity-score adjusted analysis. Ann Hepatobiliary Pancreat Surg 2019; 23: 258-264
- 32 Dalla Valle R, Cremaschi E, Lamecchi L. et al. Open and minimally invasive pancreatic neoplasms enucleation: a systematic review. Surg Endosc 2019; 33: 3192-3199
- 33 Belfiori G, Wiese D, Partelli S. et al. Minimally Invasive Versus Open Treatment for Benign Sporadic Insulinoma Comparison of Short-Term and Long-Term Outcomes. World J Surg 2018; 42: 3223-3230
- 34 Guerra F, Giuliani G, Bencini L. et al. Minimally invasive versus open pancreatic enucleation. Systematic review and meta-analysis of surgical outcomes. J Surg Oncol 2018; 117: 1509-1516
- 35 Najafi N, Mintziras I, Wiese D. et al. A retrospective comparison of robotic versus laparoscopic distal resection and enucleation for potentially benign pancreatic neoplasms. Surg Today 2020; 50: 872-880
- 36 Zhao ZM, Jiang N, Gao YX. et al. Robotic Surgery for Pancreatic Serous Cystadenoma: Analysis of 148 Cases. Sichuan Da Xue Xue Bao Yi Xue Ban 2020; 51: 467-471