J Neurol Surg A Cent Eur Neurosurg 2023; 84(01): 03-07
DOI: 10.1055/a-1832-9092
Original Article

The Role of Diskectomy in Reducing Infectious Complications after Surgery for Lumbar Spondylodiscitis

1   Department of Neurosurgery, University Medicine Göttingen Georg-August-University of Göttingen, Göttingen, Germany
,
Veit Rohde
1   Department of Neurosurgery, University Medicine Göttingen Georg-August-University of Göttingen, Göttingen, Germany
,
Tammam Abboud
1   Department of Neurosurgery, University Medicine Göttingen Georg-August-University of Göttingen, Göttingen, Germany
,
Insa Janssen
2   Department of Neurosurgery, Hospital of the Technical University Munich, Munich, Germany
3   Department of Neurosurgery, Faculté de Médecine, University Hospital Geneva, Geneva, Switzerland
,
Patrick Melich
4   Department of Neurosurgery, University Hospital Cologne, Cologne, Germany
,
2   Department of Neurosurgery, Hospital of the Technical University Munich, Munich, Germany
,
2   Department of Neurosurgery, Hospital of the Technical University Munich, Munich, Germany
5   Department of Neurosurgery, University Hospital Augsburg, Augsburg, Germany
› Author Affiliations
Funding None.

Abstract

Background Surgery for pyogenic Spondylodiscitis as an adjunct to antibiotic therapy is an established treatment. However, the technique and extent of surgical debridement remains a matter of debate. Some propagate diskectomy in all cases. Others maintain that stand-alone instrumentation is sufficient.

Methods We reviewed charts of patients who underwent instrumentation for pyogenic Spondylodiscitis with a minimum follow-up of 1 year. Patients were stratified according to whether they underwent diskectomy plus instrumentation or posterior instrumentation alone. Outcome measures included the need for surgical revision due to recurrent epidural intraspinal infection, wound revision, and construct failure.

Results In all, 257 patients who underwent surgery for pyogenic Spondylodiscitis were identified. Diskectomy and interbody procedure (group A) was performed in 102 patients, while 155 patients underwent instrumentation surgery for Spondylodiscitis without intradiskal debridement (group B). The mean age was 67 ± 12 years, and 102 patients (39.7%) were females. No significant differences were found in the need for epidural abscess recurrence therapy (group A [2.0%] and 5 cases in group B [3%; p = 0.83]) and construct failure (p = 0.575). The need for wound revisions showed a tendency toward higher rates in the posterior instrumentation–only group, which failed to reach significance (p = 0.078).

Conclusions Overall, intraspinal relapse of surgically treated pyogenic diskitis was low in our retrospective series. The choice of surgical technique was not associated with a significant difference. However, a somewhat higher rate of wound infections requiring revision in the group where no diskectomy was performed has to be weighed against a longer duration of surgery in an already ill patient population.



Publication History

Received: 31 December 2021

Accepted: 19 April 2022

Accepted Manuscript online:
22 April 2022

Article published online:
05 January 2023

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Hadjipavlou AG, Mader JT, Necessary JT, Muffoletto AJ. Hematogenous pyogenic spinal infections and their surgical management. Spine 2000; 25 (13) 1668-1679
  • 2 Bettini N, Girardo M, Dema E, Cervellati S. Evaluation of conservative treatment of non specific spondylodiscitis. Eur Spine J 2009; 18 (Suppl. 01) 143-150
  • 3 Valancius K, Hansen ES, Høy K, Helmig P, Niedermann B, Bünger C. Failure modes in conservative and surgical management of infectious spondylodiscitis. Eur Spine J 2013; 22 (08) 1837-1844
  • 4 Guerado E, Cerván AM. Surgical treatment of spondylodiscitis. An update. Int Orthop 2012; 36 (02) 413-420
  • 5 Mann S, Schütze M, Sola S, Piek J. Nonspecific pyogenic spondylodiscitis: clinical manifestations, surgical treatment, and outcome in 24 patients. Neurosurg Focus 2004; 17 (06) E3
  • 6 Shiban E, Janssen I, Wostrack M. et al. A retrospective study of 113 consecutive cases of surgically treated spondylodiscitis patients. A single-center experience. Acta Neurochir (Wien) 2014; 156 (06) 1189-1196
  • 7 Keric N, Eum DJ, Afghanyar F. et al. Evaluation of surgical strategy of conventional vs. percutaneous robot-assisted spinal trans-pedicular instrumentation in spondylodiscitis. J Robot Surg 2017; 11 (01) 17-25
  • 8 Suess O, Weise L, Brock M, Kombos T. Debridement and spinal instrumentation as a single-stage procedure in bacterial spondylitis/spondylodiscitis. Zentralbl Neurochir 2007; 68 (03) 123-132
  • 9 Korovessis P, Repantis T, Iliopoulos P, Hadjipavlou A. Beneficial influence of titanium mesh cage on infection healing and spinal reconstruction in hematogenous septic spondylitis: a retrospective analysis of surgical outcome of twenty-five consecutive cases and review of literature. Spine 2008; 33 (21) E759-E767
  • 10 Shiban E, Janssen I, da Cunha PR. et al. Safety and efficacy of polyetheretherketone (PEEK) cages in combination with posterior pedicel screw fixation in pyogenic spinal infection. Acta Neurochir (Wien) 2016; 158 (10) 1851-1857
  • 11 Tormenti MJ, Maserati MB, Bonfield CM. et al. Perioperative surgical complications of transforaminal lumbar interbody fusion: a single-center experience. J Neurosurg Spine 2012; 16 (01) 44-50
  • 12 Vakili M, Crum-Cianflone NF. Spinal epidural abscess: a series of 101 cases. Am J Med 2017; 130 (12) 1458-1463
  • 13 Uchida K, Nakajima H, Yayama T. et al. Epidural abscess associated with pyogenic spondylodiscitis of the lumbar spine; evaluation of a new MRI staging classification and imaging findings as indicators of surgical management: a retrospective study of 37 patients. Arch Orthop Trauma Surg 2010; 130 (01) 111-118
  • 14 O'Toole JE, Eichholz KM, Fessler RG. Surgical site infection rates after minimally invasive spinal surgery. J Neurosurg Spine 2009; 11 (04) 471-476
  • 15 McGirt MJ, Parker SL, Lerner J, Engelhart L, Knight T, Wang MY. Comparative analysis of perioperative surgical site infection after minimally invasive versus open posterior/transforaminal lumbar interbody fusion: analysis of hospital billing and discharge data from 5170 patients. J Neurosurg Spine 2011; 14 (06) 771-778
  • 16 Alaid A, von Eckardstein K, Smoll NR. et al. Robot guidance for percutaneous minimally invasive placement of pedicle screws for pyogenic spondylodiscitis is associated with lower rates of wound breakdown compared to conventional fluoroscopy-guided instrumentation. Neurosurg Rev 2018; 41 (02) 489-496
  • 17 Akbar M, Lehner B, Doustdar S. et al. Pyogenic spondylodiscitis of the thoracic and lumbar spine : a new classification and guide for surgical decision-making. Orthopade 2011; 40 (07) 614-623
  • 18 Pee YH, Park JD, Choi YG, Lee SH. Anterior debridement and fusion followed by posterior pedicle screw fixation in pyogenic spondylodiscitis: autologous iliac bone strut versus cage. J Neurosurg Spine 2008; 8 (05) 405-412
  • 19 Bettag C, Abboud T, von der Brelie C, Melich P, Rohde V, Schatlo B. Do we underdiagnose osteoporosis in patients with pyogenic spondylodiscitis?. Neurosurg Focus 2020; 49 (02) E16